Literature DB >> 29381422

Hodgkin Lymphoma revealed by epidural spinal cord compression.

Khalil Ghedira1, Nidhal Matar1, Sofiene Bouali1, Alia Zehani2, Adnen Boubaker1, Hafedh Jemel1.   

Abstract

CONTEXT: Hodgkin Lymphoma is rarely diagnosed as spinal cord compression syndrome. Caused by an epidural mass, this complication is often encountered in a late stage of the disease. We report the case of a 40-year-old man presenting with symptoms of low thoracic spinal cord compression due to an epidural tumor on the MRI.
FINDINGS: Emergent surgery was undertaken on this patient, consisting in laminectomy and tumor resection. After surgery, pain relief and mild neurological improvement were noticed. The histological study revealed a Hodgkin Lymphoma and the patient was referred to chemotherapy and radiotherapy.
CONCLUSION: Though chemotherapy is the gold standard treatment for Hodgkin Lymphoma, surgical spinal decompression may be required in epidural involvement of the disease. Diagnosis may be suspected in the presence of lymphadenopathy and general health decay.

Entities:  

Keywords:  Epidural; Hodgkin; Lymphoma; Spine; Surgery

Mesh:

Year:  2018        PMID: 29381422      PMCID: PMC6522921          DOI: 10.1080/10790268.2018.1427519

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  8 in total

1.  Dumbbell-shaped Hodgkin's disease with cauda equina compression mimicking a herniated inter-vertebral disc, a case report.

Authors:  Jen-Chung Liao; Tsai-Sheng Fu; Wen-Jer Chen; Shih-Ming Jung
Journal:  Chang Gung Med J       Date:  2007 Sep-Oct

2.  [Hodgkin's disease presenting with spinal cord compression].

Authors:  M Rabhi; K Ennibi; J Chaari; F Toloune
Journal:  Rev Neurol (Paris)       Date:  2007-11       Impact factor: 2.607

3.  Hodgkin's disease of the thoracic vertebrae.

Authors:  Masashi Uehara; Jun Takahashi; Hiroki Hirabayashi; Jun Kitahara; Tetsuyoshi Kamijyo; Sohei Ebara; Hiroyuki Kato
Journal:  Spine J       Date:  2013-04-23       Impact factor: 4.166

4.  Epidural spinal compression as an initial presentation of Hodgkin lymphoma.

Authors:  Nancy Abu-Bonsrah; Akwasi Ofori Boah; C Rory Goodwin; Tatianna Larman; Genevieve M Crane; Daniel M Sciubba
Journal:  J Clin Neurosci       Date:  2015-12-23       Impact factor: 1.961

Review 5.  Isolated, primary extranodal Hodgkin's disease of the spine: case report.

Authors:  J S Citow; B Rini; R Wollmann; R L Macdonald
Journal:  Neurosurgery       Date:  2001-08       Impact factor: 4.654

Review 6.  Hodgkin's disease with spinal cord compression. A case report and a review of the literature.

Authors:  S A Higgins; R E Peschel
Journal:  Cancer       Date:  1995-01-01       Impact factor: 6.860

7.  Hodgkin disease with spinal cord compression.

Authors:  Vineeta Gupta; Arvind Srivastava; Baldev Bhatia
Journal:  J Pediatr Hematol Oncol       Date:  2009-10       Impact factor: 1.289

8.  Primary epidural lymphocyte-depleted Hodgkin's lymphoma of the thoracic spine - presentation of a rare disease variant.

Authors:  Ekkehard M Kasper; Fred C Lam; Markus M Luedi; Pascal O Zinn; German A Pihan
Journal:  BMC Neurol       Date:  2012-08-03       Impact factor: 2.474

  8 in total
  1 in total

Review 1.  Hodgkin Lymphoma Presenting With Spinal Cord Compression: Challenges for Diagnosis and Initial Management.

Authors:  Nicola Bloxham; Justin Cross; Matthew Garnett; Jessica Bewick; Kate Armon; C Elizabeth Hook; Matthew J Murray
Journal:  Pediatr Dev Pathol       Date:  2021-08-24
  1 in total

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