Literature DB >> 29380466

Polyvalent Display of Biomolecules on Live Cells.

Peng Shi1, Nan Zhao1, Jinping Lai1, James Coyne1, Erin R Gaddes1, Yong Wang1.   

Abstract

Surface display of biomolecules on live cells offers new opportunities to treat human diseases and perform basic studies. Existing methods are primarily focused on monovalent functionalization, that is, the display of single biomolecules across the cell surface. Here we show that the surface of live cells can be functionalized to display polyvalent biomolecular structures through two-step reactions under physiological conditions. This polyvalent functionalization enables the cell surface to recognize the microenvironment one order of magnitude more effectively than with monovalent functionalization. Thus, polyvalent display of biomolecules on live cells holds great potential for various biological and biomedical applications.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  DNA self-assembly; cell surface engineering; molecular recognition; polyvalent display

Mesh：

Substances：

Year:  2018        PMID： 29380466      PMCID： PMC5976537          DOI： 10.1002/anie.201712596

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  37 in total

1.  Designing a polyvalent inhibitor of anthrax toxin.

Authors:  M Mourez; R S Kane; J Mogridge; S Metallo; P Deschatelets; B R Sellman; G M Whitesides; R J Collier
Journal:  Nat Biotechnol       Date:  2001-10       Impact factor: 54.908

2.  Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation.

Authors:  Gucci Jijuan Gu; Mikaela Friedman; Christian Jost; Kai Johnsson; Masood Kamali-Moghaddam; Andreas Plückthun; Ulf Landegren; Ola Söderberg
Journal:  N Biotechnol       Date:  2012-06-02       Impact factor: 5.079

3.  Cell surface-anchored fluorescent aptamer sensor enables imaging of chemical transmitter dynamics.

Authors:  Takeshi Tokunaga; Shigeyuki Namiki; Katsuhiro Yamada; Takahiro Imaishi; Hiroshi Nonaka; Kenzo Hirose; Shinsuke Sando
Journal:  J Am Chem Soc       Date:  2012-06-04       Impact factor: 15.419

4.  Selective in vivo metabolic cell-labeling-mediated cancer targeting.

Authors:  Hua Wang; Ruibo Wang; Kaimin Cai; Hua He; Yang Liu; Jonathan Yen; Zhiyu Wang; Ming Xu; Yiwen Sun; Xin Zhou; Qian Yin; Li Tang; Iwona T Dobrucki; Lawrence W Dobrucki; Eric J Chaney; Stephen A Boppart; Timothy M Fan; Stéphane Lezmi; Xuesi Chen; Lichen Yin; Jianjun Cheng
Journal:  Nat Chem Biol       Date:  2017-02-13       Impact factor: 15.040

Review 5.  Nanomaterials. Programmable materials and the nature of the DNA bond.

Authors:  Matthew R Jones; Nadrian C Seeman; Chad A Mirkin
Journal:  Science       Date:  2015-02-20       Impact factor: 47.728

6.  Cell-surface engineering by a conjugation-and-release approach based on the formation and cleavage of oxime linkages upon mild electrochemical oxidation and reduction.

Authors:  Abigail Pulsipher; Debjit Dutta; Wei Luo; Muhammad N Yousaf
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-07       Impact factor: 15.336

Review 7.  Cu-free click cycloaddition reactions in chemical biology.

Authors:  John C Jewett; Carolyn R Bertozzi
Journal:  Chem Soc Rev       Date:  2010-04       Impact factor: 54.564

8.  Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.

Authors:  G Gross; T Waks; Z Eshhar
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

9.  Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA.

Authors:  Chenxiang Lin; Ralf Jungmann; Andrew M Leifer; Chao Li; Daniel Levner; George M Church; William M Shih; Peng Yin
Journal:  Nat Chem       Date:  2012-10       Impact factor: 24.427

10.  Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.

Authors:  Heebeom Koo; Myunghwan Choi; Eunha Kim; Sei Kwang Hahn; Ralph Weissleder; Seok Hyun Yun
Journal:  Small       Date:  2015-11-19       Impact factor: 13.281
View more
  5 in total

1.  Supramolecular "Click Chemistry" for Targeting in the Body.

Authors:  Christopher J Addonizio; Brant D Gates; Matthew J Webber
Journal:  Bioconjug Chem       Date:  2021-08-20       Impact factor: 6.069

2.  DNA nanotweezers for stabilizing and dynamically lighting up a lipid raft on living cell membranes and the activation of T cells.

Authors:  Lele Sun; Yingying Su; Jun-Gang Wang; Fei Xia; Ying Xu; Di Li
Journal:  Chem Sci       Date:  2020-01-07       Impact factor: 9.825

3.  Orthogonal Blue and Red Light Controlled Cell-Cell Adhesions Enable Sorting-out in Multicellular Structures.

Authors:  Samaneh Rasoulinejad; Marc Mueller; Brice Nzigou Mombo; Seraphine V Wegner
Journal:  ACS Synth Biol       Date:  2020-07-16       Impact factor: 5.110

Review 4.  DNA-Based Molecular Engineering of the Cell Membrane.

Authors:  Xiaodong Li; Tiantian Wang; Yue Sun; Chang Li; Tianhuan Peng; Liping Qiu
Journal:  Membranes (Basel)       Date:  2022-01-19

5.  The Importance of Cell-Cell Interaction Dynamics in Bottom-Up Tissue Engineering: Concepts of Colloidal Self-Assembly in the Fabrication of Multicellular Architectures.

Authors:  Marc Mueller; Samaneh Rasoulinejad; Sukant Garg; Seraphine V Wegner
Journal:  Nano Lett       Date:  2019-11-25       Impact factor: 11.189
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.