F Z Mokrane1,2, L Dercle3,4, O Meyrignac5, É Crubézy6, H Rousseau5, N Telmon6,7, F Dedouit6,8. 1. Radiology Department, Rangueil University Hospital, 1 Avenue du Professeur Jean Poulhes, 31059 cedex, Toulouse, France. mokrane_fatimazohra@yahoo.fr. 2. French National Center for Scientific Research, AMIS Laboratory: University of Toulouse, UMR 5288, 37 allées Jules Guesde, 31073, Toulouse, France. mokrane_fatimazohra@yahoo.fr. 3. Gustave Roussy Institute, Université Paris-Saclay, F-94805, Villejuif, France. 4. New York Presbyterian Hospital, Columbia University, New York, NY, 10039, USA. 5. Radiology Department, Rangueil University Hospital, 1 Avenue du Professeur Jean Poulhes, 31059 cedex, Toulouse, France. 6. French National Center for Scientific Research, AMIS Laboratory: University of Toulouse, UMR 5288, 37 allées Jules Guesde, 31073, Toulouse, France. 7. Forensic Department, Rangueil University Hospital, 1 avenue du Professeur Jean Poulhes. 31059 cedex, Toulouse, France. 8. Unit of Forensic and Anthropological Imaging, Centre universitaire romand de médecine légale (CURML), Chemin de la Vulliette 4, CH-1000, Lausanne 25, Switzerland.
Abstract
PURPOSE: Multi-phase postmortem computed tomography angiography (MPMCTA) is a growing technique, which is standardized for adults. Application of this protocol for a children population is not so well defined. Our study aims to adapt the adult's protocol to children, using a porcine model. MATERIAL AND METHODS: Three groups of 18 pigs were studied, with a weight distribution between 4 and 48 kg. Different pump devices were used. Pigs of group I were studied using the Virtangio® machine, whereas pigs of groups II and III were studied using used the Medrad® machine. Study of vascular opacification was possible using a semi-quantitative method based on 26 arterial and 26 venous segments that were distributed over the entire body from the cephalic extremity to the posterior pawns. RESULTS: While thoracic, abdominal, and pelvic vascular opacification were complete for each individual pig in a group, group III showed better vascular opacification for the cephalic extremity. This was also true for anterior and posterior pawns vascular opacification. Spearman correlation tests showed a significant relationship between anthropometric characteristics of pigs, injection parameters, and percentage of opacified segments. A higher percentage of opacification was obtained for individuals of lower weights, with comparatively lower quantities of contrast agent injected. CONCLUSION: Postmortem computed tomography angiography (PMCTA) was possible for all the individuals, particularly for small weights (4 kg) using the Medrad® machine. However, further studies are needed to better understand the procedure.
PURPOSE: Multi-phase postmortem computed tomography angiography (MPMCTA) is a growing technique, which is standardized for adults. Application of this protocol for a children population is not so well defined. Our study aims to adapt the adult's protocol to children, using a porcine model. MATERIAL AND METHODS: Three groups of 18 pigs were studied, with a weight distribution between 4 and 48 kg. Different pump devices were used. Pigs of group I were studied using the Virtangio® machine, whereas pigs of groups II and III were studied using used the Medrad® machine. Study of vascular opacification was possible using a semi-quantitative method based on 26 arterial and 26 venous segments that were distributed over the entire body from the cephalic extremity to the posterior pawns. RESULTS: While thoracic, abdominal, and pelvic vascular opacification were complete for each individual pig in a group, group III showed better vascular opacification for the cephalic extremity. This was also true for anterior and posterior pawns vascular opacification. Spearman correlation tests showed a significant relationship between anthropometric characteristics of pigs, injection parameters, and percentage of opacified segments. A higher percentage of opacification was obtained for individuals of lower weights, with comparatively lower quantities of contrast agent injected. CONCLUSION: Postmortem computed tomography angiography (PMCTA) was possible for all the individuals, particularly for small weights (4 kg) using the Medrad® machine. However, further studies are needed to better understand the procedure.
Authors: F-Z Mokrane; F Savall; C Rérolle; A Blanc; P Saint Martin; H Rousseau; D Rougé; N Telmon; F Dedouit Journal: Diagn Interv Imaging Date: 2014-11 Impact factor: 4.026
Authors: Beatrice Vogel; Axel Heinemann; Helmut Gulbins; Hendrik Treede; Hermann Reichenspurner; Klaus Püschel; Hermann Vogel Journal: Eur J Cardiothorac Surg Date: 2015-02-16 Impact factor: 4.191
Authors: Anna Zamir; Owen J Arthurs; Charlotte K Hagen; Paul C Diemoz; Thierry Brochard; Alberto Bravin; Neil J Sebire; Alessandro Olivo Journal: Br J Radiol Date: 2015-11-27 Impact factor: 3.039