Eunji Bang1, Kai Tanabe2, Noriko Yokoyama3, Shoko Chijiki1, Takuya Tsuruzono4, Shinya Kuno5,6. 1. Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan. 2. Faculty of Human Health Department of Health and Nutrition Sciences, Komazawa Women's University, 238 Sakahama, Inagi, Tokyo, 206-8511, Japan. 3. Sport and Health Promotion, Graduate School Master's Program, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-ku, Tokyo, 112-0012, Japan. 4. Tsukuba Wellness Research Co., Ltd, 178-4 Wakashiba, Kashiwa, Chiba, 277-8519, Japan. 5. Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan. kuno.shinya.gb@u.tsukuba.ac.jp. 6. Tsukuba Wellness Research Co., Ltd, 178-4 Wakashiba, Kashiwa, Chiba, 277-8519, Japan. kuno.shinya.gb@u.tsukuba.ac.jp.
Abstract
PURPOSE: Intermuscular adipose tissue (IMAT) accumulates with age. However, there has been no long-term intervention study examining whether daily walking prevents or decreases the age-related IMAT accumulation. The purpose of this study was to determine effects of a long-term lifestyle-based daily walking program on age-related IMAT accumulation after a 5-year follow-up. METHODS: Using a pedometer, daily step count was evaluated for 5 years in 24 middle-aged and elderly male and female participants. Using magnetic resonance imaging, thigh muscle, thigh subcutaneous adipose tissue, IMAT, abdominal subcutaneous adipose tissue, and visceral adipose tissue were examined at baseline and after 5 years. RESULTS: After 5 years, there was no significant increase in IMAT in all participants. In addition, IMAT significantly decreased in participants with a daily step count of > 9000 (4.0 ± 2.1 vs. 3.1 ± 1.6 cm2; p < 0.05). Moreover, changes in IMAT within 5 years correlated with changes in daily step counts, even after adjusting for confounding factors (p < 0.05). CONCLUSIONS: Long-term lifestyle-based daily walking program prevented the age-related IMAT accumulation in middle-aged and elderly adults. Furthermore, increased daily walking correlated with decreased IMAT over 5 years.
PURPOSE: Intermuscular adipose tissue (IMAT) accumulates with age. However, there has been no long-term intervention study examining whether daily walking prevents or decreases the age-related IMAT accumulation. The purpose of this study was to determine effects of a long-term lifestyle-based daily walking program on age-related IMAT accumulation after a 5-year follow-up. METHODS: Using a pedometer, daily step count was evaluated for 5 years in 24 middle-aged and elderly male and female participants. Using magnetic resonance imaging, thigh muscle, thigh subcutaneous adipose tissue, IMAT, abdominal subcutaneous adipose tissue, and visceral adipose tissue were examined at baseline and after 5 years. RESULTS: After 5 years, there was no significant increase in IMAT in all participants. In addition, IMAT significantly decreased in participants with a daily step count of > 9000 (4.0 ± 2.1 vs. 3.1 ± 1.6 cm2; p < 0.05). Moreover, changes in IMAT within 5 years correlated with changes in daily step counts, even after adjusting for confounding factors (p < 0.05). CONCLUSIONS: Long-term lifestyle-based daily walking program prevented the age-related IMAT accumulation in middle-aged and elderly adults. Furthermore, increased daily walking correlated with decreased IMAT over 5 years.
Entities:
Keywords:
Aging; Daily walking; Intermuscular adipose tissue; Skeletal muscle mass
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