Literature DB >> 2937645

Relaxant profile of synthetic atrial natriuretic factor on guinea-pig pulmonary tissues.

R Hamel, A W Ford-Hutchinson.   

Abstract

Synthetic atrial natriuretic factor (ANF) (3.22 X 10(-7)-9.67 X 10(-9) M) produced relaxation of the intrinsic and extrinsic tone of the guinea-pig trachea. ANF was more potent on the trachea as compared to the parenchyma of the guinea-pig. On the trachea ANF was a more potent relaxant of intrinsic tonus or contractions induced by methacholine as compared to contractions induced by leukotriene D4. When administered by aerosol to anesthetized spontaneously breathing guinea-pigs, ANF produced neither bronchodilation nor inhibition of bronchoconstriction induced by an aerosol of leukotriene D4.

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Year:  1986        PMID： 2937645     DOI： 10.1016/0014-2999(86)90406-1

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  7 in total

1.  Bronchodilator effect of atrial natriuretic peptide in asthma.

Authors:  G Hulks; A Jardine; J M Connell; N C Thomson
Journal:  BMJ       Date:  1989-10-28

2.  Localization of the bronchodilator effect induced by type A natriuretic peptide in asthmatic subjects.

Authors:  T Flüge; H Fabel; T O Wagner; W G Forssmann
Journal:  Clin Investig       Date:  1994-10

3.  Muscarinic effect of atrial natriuretic peptide on rabbit airways.

Authors:  A Robichaud; C Saunier; M C Michoud; P du Souich
Journal:  Br J Pharmacol       Date:  1993-10       Impact factor: 8.739

4.  Circulating plasma concentrations of atrial natriuretic peptide and catecholamines in response to maximal exercise in normal and asthmatic subjects.

Authors:  G Hulks; A F Mohammed; A G Jardine; J M Connell; N C Thomson
Journal:  Thorax       Date:  1991-11       Impact factor: 9.139

5.  Atrial and brain natriuretic peptides share binding sites on cultured cells from the rat trachea.

Authors:  S James; G Burnstock
Journal:  Cell Tissue Res       Date:  1991-09       Impact factor: 5.249

6.  Glucagon-Like Peptide 1 and Atrial Natriuretic Peptide in a Female Mouse Model of Obstructive Pulmonary Disease.

Authors:  Emilie Balk-Møller; Johanne Agerlin Windeløv; Berit Svendsen; Jenna Hunt; Seyed Mojtaba Ghiasi; Charlotte Mehlin Sørensen; Jens Juul Holst; Hannelouise Kissow
Journal:  J Endocr Soc       Date:  2019-12-19

7.  Influence of atrial natriuretic peptide, brain natriuretic peptide and urodilatin on the histamine-induced bronchoconstriction in the conscious guinea pig.

Authors:  M Hermel
Journal:  Inflammopharmacology       Date:  1998       Impact factor: 5.093
  7 in total

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