Literature DB >> 29374798

Exophiala dermatitidis Endophthalmitis: Case Report and Literature Review.

Mónika Homa1,2, Palanisamy Manikandan3,4,5, Veerappan Saravanan3, Rajaraman Revathi3, Raghavan Anita3, Venkatapathy Narendran3, Kanesan Panneerselvam6, Coimbatore Subramanian Shobana7, Mohammed Al Aidarous4, László Galgóczy2, Csaba Vágvölgyi2, Tamás Papp8,9, László Kredics2.   

Abstract

We report a case of a 59-year-old male patient with a postoperative fungal infection of the left eye. A dark-pigmented yeast, Exophiala dermatitidis (previously known as Wangiella dermatitidis), was identified from the culture of the biopsy taken from the posterior capsule. The infection was successfully eradicated by a combination of surgical and medical (i.e., voriconazole and fluconazole) treatment. This is the first report of successfully treated E. dermatitidis endophthalmitis, which demonstrates that a prompt and aggressive antifungal therapy combined with surgical intervention is necessary to prevent vision loss in cases of endophthalmitis due to Exophiala species. Beside the case description, we also aim to provide a literature review of previously reported eye infections caused by Exophiala species in order to help the future diagnosis and management of the disease.

Entities:  

Keywords:  Antifungal susceptibility; Dematiaceous fungi; Endophthalmitis; Exophiala; Keratitis

Mesh:

Substances:

Year:  2018        PMID: 29374798     DOI: 10.1007/s11046-017-0235-4

Source DB:  PubMed          Journal:  Mycopathologia        ISSN: 0301-486X            Impact factor:   2.574


  24 in total

1.  Corneal phaeohyphomycosis caused by Wangiella dermatitidis.

Authors:  L Pospísil; S Skorkovská; M Moster
Journal:  Ophthalmologica       Date:  1990       Impact factor: 3.250

2.  Exophiala jeanselmei keratitis after laser in situ keratomileusis.

Authors:  Eric H Leung; Risha Moskalewicz; Jorge P Parada; Kevin J Kovach; Charles Bouchard
Journal:  J Cataract Refract Surg       Date:  2008-10       Impact factor: 3.351

3.  Fusarium keratitis in South India: causative agents, their antifungal susceptibilities and a rapid identification method for the Fusarium solani species complex.

Authors:  Mónika Homa; Coimbatore S Shobana; Yendrembam R B Singh; Palanisamy Manikandan; Kanesan P Selvam; László Kredics; Venkatapathy Narendran; Csaba Vágvölgyi; László Galgóczy
Journal:  Mycoses       Date:  2013-02-26       Impact factor: 4.377

4.  Delayed-onset postoperative endophthalmitis secondary to Exophiala.

Authors:  Jose Alberto Quintero-Estades; Scott Walter; Felipe Valenzuela; Guillermo Amescua
Journal:  BMJ Case Rep       Date:  2015-02-17

5.  High rate of Exophiala dermatitidis recovery in the airways of patients with cystic fibrosis is associated with pancreatic insufficiency.

Authors:  Nahid Kondori; Marita Gilljam; Anders Lindblad; Bodil Jönsson; Edward R B Moore; Christine Wennerås
Journal:  J Clin Microbiol       Date:  2011-01-05       Impact factor: 5.948

6.  A new DNA sequence assembly program.

Authors:  J K Bonfield; K f Smith; R Staden
Journal:  Nucleic Acids Res       Date:  1995-12-25       Impact factor: 16.971

7.  Chronic exogenous exophiala dermatitidis endophthalmitis.

Authors:  Michael F Clamp; J Michael Jumper; Christine W Ku; H Richard McDonald; Robert N Johnson; Arthur D Fu; Brandon J Lujan; Emmett T Cunningham
Journal:  Retin Cases Brief Rep       Date:  2014

8.  Epidemiology of Aspergillus keratitis at a tertiary care eye hospital in South India and antifungal susceptibilities of the causative agents.

Authors:  Palanisamy Manikandan; János Varga; Sándor Kocsubé; Raghavan Anita; Rajaraman Revathi; Tibor Mihály Németh; Venkatapathy Narendran; Csaba Vágvölgyi; Kanesan Panneer Selvam; Coimbatore Subramanian Shobana; Yendremban Randhir Babu Singh; László Kredics
Journal:  Mycoses       Date:  2012-04-10       Impact factor: 4.377

9.  Spectrum of clinically relevant Exophiala species in the United States.

Authors:  J S Zeng; D A Sutton; A W Fothergill; M G Rinaldi; M J Harrak; G S de Hoog
Journal:  J Clin Microbiol       Date:  2007-06-27       Impact factor: 5.948

10.  Molecular identification and antifungal susceptibility of Curvularia australiensis, C. hawaiiensis and C. spicifera isolated from human eye infections.

Authors:  Krisztina Krizsán; Eszter Tóth; László G Nagy; László Galgóczy; Palanisamy Manikandan; Muthusamy Chandrasekaran; Shine Kadaikunnan; Naiyf S Alharbi; Csaba Vágvölgyi; Tamás Papp
Journal:  Mycoses       Date:  2015-09-08       Impact factor: 4.377

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  8 in total

1.  Endogenous Exophiala dermatitidis endophthalmitis.

Authors:  Manuela Gutierrez-Velez; Amber Hoang; Jessica Weinstein; Keegan Harkins; Rajiv Shah
Journal:  Am J Ophthalmol Case Rep       Date:  2020-06-06

2.  Peritonitis by Exophiala dermatitidis in a pediatric patient.

Authors:  Rosângela L Pinheiro; Regielly C R Cognialli; Rodolfo C Barros; Tyane de A Pinto; Mariana F M Cunha; Tony T Tahan; Morgana F Voidaleski; Renata R Gomes; Guilherme N Becker; Lucas V Andrade; Flavio Queiroz-Telles; G Sybren de Hoog; Renata R Sakiyama; Vânia A Vicente
Journal:  Med Mycol Case Rep       Date:  2019-02-15

3.  A fatal neonatal case of fungemia due to Exophiala dermatitidis-case report and literature review.

Authors:  Alexandra Mpakosi; Maria Siopi; Maria Demetriou; Vasiliki Falaina; Martha Theodoraki; Joseph Meletiadis
Journal:  BMC Pediatr       Date:  2022-08-10       Impact factor: 2.567

4.  Identification of microbial agents in tissue specimens of ocular and periocular sarcoidosis using a metagenomics approach.

Authors:  Amde Selassie Shifera; Christopher Pockrandt; Natalia Rincon; Yuchen Ge; Jennifer Lu; Ales Varabyou; Anne E Jedlicka; Karen Sun; Alan L Scott; Charles Eberhart; Jennifer E Thorne; Steven L Salzberg
Journal:  F1000Res       Date:  2021-08-17

Review 5.  Practical Guidance for Clinical Microbiology Laboratories: Diagnosis of Ocular Infections.

Authors:  Sixto M Leal; Kyle G Rodino; W Craig Fowler; Peter H Gilligan
Journal:  Clin Microbiol Rev       Date:  2021-06-02       Impact factor: 50.129

6.  Exophiala Keratitis following Descemet Stripping Automated Endothelial Keratoplasty.

Authors:  Ana Marta; Paula Costa; Virgínia Lopes; Miguel Mesquita Neves; Miguel Gomes; Luís Oliveira
Journal:  Case Rep Ophthalmol Med       Date:  2020-10-29

7.  Delayed-onset post-operative keratitis and endophthalmitis caused by Exophiala oligosperma.

Authors:  Laurie W van der Merwe; Dawood da Costa; Kessendri Reddy; David Meyer
Journal:  J Ophthalmic Inflamm Infect       Date:  2021-12-23

8.  A retrospective 'real-world' cohort study of azole therapeutic drug monitoring and evolution of antifungal resistance in cystic fibrosis.

Authors:  M Di Paolo; L Hewitt; E Nwanko; M Ni; A Vidal-Diaz; M C Fisher; D Armstrong-James; A Shah
Journal:  JAC Antimicrob Resist       Date:  2021-03-16
  8 in total

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