| Literature DB >> 29373928 |
Yu Zhu1,2, Liao-Bin Dong1, Zhi-Jun Zhang1,2, Min Fan1, Qin-Feng Zhu1,2, Yan-Yan Qi1,2, Yu-Chen Liu1,2, Li-Yan Peng1, Xing-De Wu1, Qin-Shi Zhao1.
Abstract
Three new Lycopodium alkaloids (1-3), together with 15 known alkaloids, were isolated from club moss Lycopodium japonicum. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR spectra. Compound 1 has an unusual β-oriented methyl group substituted at C-15 and an α-hydroxy cyclopentenone moiety. All new alkaloids were evaluated for the inhibition of T-type calcium channel.Entities:
Keywords: alkaloids; Lycopodiaceae; T-type calcium channel
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Year: 2018 PMID： 29373928 DOI： 10.1080/10286020.2018.1427075
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569