| Literature DB >> 29373673 |
Ibukunoluwa C Akinboyo1, Genevieve M Crane2, Lingling Chen1, Ravit Arav-Boger1.
Abstract
Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.Entities:
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Year: 2018 PMID: 29373673 PMCID: PMC6276027 DOI: 10.1093/jpids/pix101
Source DB: PubMed Journal: J Pediatric Infect Dis Soc ISSN: 2048-7193 Impact factor: 3.164