Hitomi Iwasa1, Yoriko Murata2, Miki Nishimori2, Kana Miyatake2, Michiko Tadokoro2, Shino Kohsaki3, Munenobu Nogami4, Yusuke Ueba5, Tetsuya Ueba5, Takuji Yamagami2. 1. Department of Radiology, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku, Kochi, 783-8505, Japan. iwasah@kochi-u.ac.jp. 2. Department of Radiology, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku, Kochi, 783-8505, Japan. 3. Department of Radiology, Health care system JINSEI-KAI Hosogi Hospital, Daizencho, Kochi, Kochi, 780-0926, Japan. 4. Department of Radiology, Kobe University Hospital, Kusunokicho Chuoku, Kobe, Hyogo, 650-0017, Japan. 5. Department of Neurosurgery, Kochi Medical School, Kochi University, Kohasu, Okocho, Nankoku, Kochi, 783-8505, Japan.
Abstract
PURPOSE: To evaluate reduced metabolism in the ipsilateral thalamus (TH) and/or contralateral cerebellum (CE) according to tumor localization and cortical metabolism around the tumor in patients with brain tumors based on FDG uptake. METHODS: This study investigated 48 consecutive patients with solitary cerebral hemisphere parenchymal brain tumors who underwent PET/CT and MRI. Patients were divided into 4 groups (A: reduced uptake in ipsilateral TH and contralateral CE, B: reduced uptake in ipsilateral TH only, C: reduced uptake in contralateral CE only, and D: no reduced uptake in ipsilateral TH or contralateral CE). FDG uptake and MRI findings were compared among these groups. RESULTS: Of 48 patients, group A included 24 (50%), group B included 10 (21%), group C included 0, and group D included 14 (29%). No significant tendencies were observed between the groups regarding tumor localization. However, reduced cortical metabolism around the tumor was observed in 22 patients in group A, 7 patients in group B, and 1 patient in group D. All patients in group B showed reduced metabolism from around the tumor up to the ipsilateral TH. CONCLUSION: Reduced FDG uptake in ipsilateral TH and contralateral CE usually occur simultaneously in patients with solitary brain tumors.
PURPOSE: To evaluate reduced metabolism in the ipsilateral thalamus (TH) and/or contralateral cerebellum (CE) according to tumor localization and cortical metabolism around the tumor in patients with brain tumors based on FDG uptake. METHODS: This study investigated 48 consecutive patients with solitary cerebral hemisphere parenchymal brain tumors who underwent PET/CT and MRI. Patients were divided into 4 groups (A: reduced uptake in ipsilateral TH and contralateral CE, B: reduced uptake in ipsilateral TH only, C: reduced uptake in contralateral CE only, and D: no reduced uptake in ipsilateral TH or contralateral CE). FDG uptake and MRI findings were compared among these groups. RESULTS: Of 48 patients, group A included 24 (50%), group B included 10 (21%), group C included 0, and group D included 14 (29%). No significant tendencies were observed between the groups regarding tumor localization. However, reduced cortical metabolism around the tumor was observed in 22 patients in group A, 7 patients in group B, and 1 patient in group D. All patients in group B showed reduced metabolism from around the tumor up to the ipsilateral TH. CONCLUSION: Reduced FDG uptake in ipsilateral TH and contralateral CE usually occur simultaneously in patients with solitary brain tumors.
Authors: A Otte; U Roelcke; K von Ammon; O Hausmann; R P Maguire; J Missimer; J Müller-Brand; E W Radü; K L Leenders Journal: J Neurol Sci Date: 1998 Impact factor: 3.181
Authors: N J Patronas; G Di Chiro; B H Smith; R De La Paz; R A Brooks; H L Milam; P L Kornblith; D Bairamian; L Mansi Journal: Brain Res Date: 1984-01-16 Impact factor: 3.252