Literature DB >> 29371420

Should We Increase GFR with Bardoxolone in Alport Syndrome?

Colin Baigent1, Rachel Lennon2,3.   

Abstract

Entities:  

Keywords:  Alport-s syndrome; glomerular hyperfiltration; progression of chronic renal failure; renin angiotensin system

Mesh：

Substances：

Year:  2018        PMID： 29371420      PMCID： PMC5791073          DOI： 10.1681/ASN.2017101062

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


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  8 in total

1.  Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts.

Authors:  Ron T Gansevoort; Kunihiro Matsushita; Marije van der Velde; Brad C Astor; Mark Woodward; Andrew S Levey; Paul E de Jong; Josef Coresh
Journal:  Kidney Int       Date:  2011-02-02       Impact factor: 10.612

2.  Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease.

Authors:  Dick de Zeeuw; Tadao Akizawa; Paul Audhya; George L Bakris; Melanie Chin; Heidi Christ-Schmidt; Angie Goldsberry; Mark Houser; Melissa Krauth; Hiddo J Lambers Heerspink; John J McMurray; Colin J Meyer; Hans-Henrik Parving; Giuseppe Remuzzi; Robert D Toto; Nosratola D Vaziri; Christoph Wanner; Janet Wittes; Danielle Wrolstad; Glenn M Chertow
Journal:  N Engl J Med       Date:  2013-11-09       Impact factor: 91.245

Review 3.  Drug-Induced Reduction in Albuminuria Is Associated with Subsequent Renoprotection: A Meta-Analysis.

Authors:  Hiddo J Lambers Heerspink; Tobias F Kröpelin; Jarno Hoekman; Dick de Zeeuw
Journal:  J Am Soc Nephrol       Date:  2014-11-24       Impact factor: 10.121

4.  A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.

Authors:  David S Hong; Razelle Kurzrock; Jeffrey G Supko; Xiaoying He; Aung Naing; Jennifer Wheler; Donald Lawrence; Joseph Paul Eder; Colin J Meyer; Deborah A Ferguson; James Mier; Marina Konopleva; Sergej Konoplev; Michael Andreeff; Donald Kufe; Hillard Lazarus; Geoffrey I Shapiro; Bruce J Dezube
Journal:  Clin Cancer Res       Date:  2012-05-25       Impact factor: 12.531

5.  Bardoxolone methyl and kidney function in CKD with type 2 diabetes.

Authors:  Pablo E Pergola; Philip Raskin; Robert D Toto; Colin J Meyer; J Warren Huff; Eric B Grossman; Melissa Krauth; Stacey Ruiz; Paul Audhya; Heidi Christ-Schmidt; Janet Wittes; David G Warnock
Journal:  N Engl J Med       Date:  2011-06-24       Impact factor: 91.245

6.  The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin.

Authors:  A Besarab; W K Bolton; J K Browne; J C Egrie; A R Nissenson; D M Okamoto; S J Schwab; D A Goodkin
Journal:  N Engl J Med       Date:  1998-08-27       Impact factor: 91.245

7.  Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease-Improving Global Outcomes (KDIGO) Controversies Conference.

Authors:  Colin Baigent; William G Herrington; Josef Coresh; Martin J Landray; Adeera Levin; Vlado Perkovic; Marc A Pfeffer; Peter Rossing; Michael Walsh; Christoph Wanner; David C Wheeler; Wolfgang C Winkelmayer; John J V McMurray
Journal:  Kidney Int       Date:  2017-08       Impact factor: 10.612

Review 8.  Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease.

Authors:  Stacey Ruiz; Pablo E Pergola; Richard A Zager; Nosratola D Vaziri
Journal:  Kidney Int       Date:  2013-01-16       Impact factor: 10.612
  8 in total
  10 in total

1.  Editorial Note: From Both Sides Now.

Authors:  Josephine P Briggs; Thomas H Hostetter
Journal:  J Am Soc Nephrol       Date:  2018-01-25       Impact factor: 10.121

2.  Emerging drugs for treatment of focal segmental glomerulosclerosis.

Authors:  Howard Trachtman
Journal:  Expert Opin Emerg Drugs       Date:  2020-08-12       Impact factor: 4.191

3.  Acute Treatment Effects on GFR in Randomized Clinical Trials of Kidney Disease Progression.

Authors:  Brendon L Neuen; Hocine Tighiouart; Hiddo J L Heerspink; Edward F Vonesh; Juhi Chaudhari; Shiyuan Miao; Tak Mao Chan; Fernando C Fervenza; Jürgen Floege; Marian Goicoechea; William G Herrington; Enyu Imai; Tazeen H Jafar; Julia B Lewis; Philip Kam-Tao Li; Francesco Locatelli; Bart D Maes; Ronald D Perrone; Manuel Praga; Annalisa Perna; Francesco P Schena; Christoph Wanner; Jack F M Wetzels; Mark Woodward; Di Xie; Tom Greene; Lesley A Inker
Journal:  J Am Soc Nephrol       Date:  2021-12-03       Impact factor: 10.121

Review 4.  Nephron overload as a therapeutic target to maximize kidney lifespan.

Authors:  Valerie A Luyckx; Andrew D Rule; Katherine R Tuttle; Pierre Delanaye; Helen Liapis; Afschin Gandjour; Paola Romagnani; Hans-Joachim Anders
Journal:  Nat Rev Nephrol       Date:  2021-12-08       Impact factor: 42.439

Review 5.  Oxidative stress and redox signaling in CRPC progression: therapeutic potential of clinically-tested Nrf2-activators.

Authors:  Debasis Mondal; Devin Narwani; Shahnawaz Notta; Dawood Ghaffar; Nikhil Mardhekar; Syed S A Quadri
Journal:  Cancer Drug Resist       Date:  2021-03-19

Review 6.  Deleting Death and Dialysis: Conservative Care of Cardio-Vascular Risk and Kidney Function Loss in Chronic Kidney Disease (CKD).

Authors:  Raymond Vanholder; Steven Van Laecke; Griet Glorieux; Francis Verbeke; Esmeralda Castillo-Rodriguez; Alberto Ortiz
Journal:  Toxins (Basel)       Date:  2018-06-12       Impact factor: 4.546

Review 7.  Eat Your Broccoli: Oxidative Stress, NRF2, and Sulforaphane in Chronic Kidney Disease.

Authors:  Scott E Liebman; Thu H Le
Journal:  Nutrients       Date:  2021-01-18       Impact factor: 5.717

Review 8.  Molecular Mechanisms in Early Diabetic Kidney Disease: Glomerular Endothelial Cell Dysfunction.

Authors:  Emelie Lassén; Ilse S Daehn
Journal:  Int J Mol Sci       Date:  2020-12-11       Impact factor: 5.923

Review 9.  The glomerular filtration barrier: a structural target for novel kidney therapies.

Authors:  Ilse S Daehn; Jeremy S Duffield
Journal:  Nat Rev Drug Discov       Date:  2021-07-14       Impact factor: 84.694

Review 10.  Basement membrane collagens and disease mechanisms.

Authors:  Anna Gatseva; Yuan Yan Sin; Gaia Brezzo; Tom Van Agtmael
Journal:  Essays Biochem       Date:  2019-09-13       Impact factor: 8.000
  10 in total

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