| Literature DB >> 29369149 |
Angela Nalwoga1,2, Wendell Miley3, Nazzarena Labo3, Alison Elliott1,2, Stephen Cose1,2, Denise Whitby3, Robert Newton1,4.
Abstract
We investigated associations between Kaposi sarcoma-associated herpesvirus (KSHV) seroconversion age and KSHV antibody values in Ugandan children. Every annual delay in KSHV seroconversion age was associated with a reduction of 19% (P < 0.0001) in K8.1 and 27% (P < 0.0001) in ORF73 antibody values at 6 years of age. Early infection may be an important risk factor for KSHV pathogenesis and viral shedding in saliva, leading to transmission.Entities:
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Year: 2018 PMID: 29369149 PMCID: PMC6010155 DOI: 10.1097/INF.0000000000001909
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN: 0891-3668 Impact factor: 2.129