Literature DB >> 29369149

Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda.

Angela Nalwoga1,2, Wendell Miley3, Nazzarena Labo3, Alison Elliott1,2, Stephen Cose1,2, Denise Whitby3, Robert Newton1,4.   

Abstract

We investigated associations between Kaposi sarcoma-associated herpesvirus (KSHV) seroconversion age and KSHV antibody values in Ugandan children. Every annual delay in KSHV seroconversion age was associated with a reduction of 19% (P < 0.0001) in K8.1 and 27% (P < 0.0001) in ORF73 antibody values at 6 years of age. Early infection may be an important risk factor for KSHV pathogenesis and viral shedding in saliva, leading to transmission.

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Year:  2018        PMID: 29369149      PMCID: PMC6010155          DOI: 10.1097/INF.0000000000001909

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  9 in total

1.  Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study.

Authors:  G de-Thé; A Geser; N E Day; P M Tukei; E H Williams; D P Beri; P G Smith; A G Dean; G W Bronkamm; P Feorino; W Henle
Journal:  Nature       Date:  1978-08-24       Impact factor: 49.962

2.  Early age at time of primary Epstein-Barr virus infection results in poorly controlled viral infection in infants from Western Kenya: clues to the etiology of endemic Burkitt lymphoma.

Authors:  Erwan Piriou; Amolo S Asito; Peter O Sumba; Nancy Fiore; Jaap M Middeldorp; Ann M Moormann; Robert Ploutz-Snyder; Rosemary Rochford
Journal:  J Infect Dis       Date:  2012-02-01       Impact factor: 5.226

3.  The sero-epidemiology of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in adults with cancer in Uganda.

Authors:  Robert Newton; John Ziegler; Dimitra Bourboulia; Delphine Casabonne; Valerie Beral; Edward Mbidde; Lucy Carpenter; Gillian Reeves; D Maxwell Parkin; Henry Wabinga; Sam Mbulaiteye; Harold Jaffe; Robin Weiss; Chris Boshoff
Journal:  Int J Cancer       Date:  2003-01-10       Impact factor: 7.396

4.  Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children.

Authors:  Ann M Moormann; Kiprotich Chelimo; Peter O Sumba; Daniel J Tisch; Rosemary Rochford; James W Kazura
Journal:  J Infect Dis       Date:  2007-02-06       Impact factor: 5.226

5.  The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood [ISRCTN32849447].

Authors:  Alison M Elliott; Moses Kizza; Maria A Quigley; Juliet Ndibazza; Margaret Nampijja; Lawrence Muhangi; Linda Morison; Proscovia B Namujju; Moses Muwanga; Narcis Kabatereine; James A G Whitworth
Journal:  Clin Trials       Date:  2007       Impact factor: 2.486

6.  Human herpesvirus 8 infection within families in rural Tanzania.

Authors:  Sam M Mbulaiteye; Ruth M Pfeiffer; Denise Whitby; Glen R Brubaker; John Shao; Robert J Biggar
Journal:  J Infect Dis       Date:  2003-06-01       Impact factor: 5.226

7.  Detection of antibodies to human herpesvirus 8 in Italian children: evidence for horizontal transmission.

Authors:  D Whitby; M Luppi; C Sabin; P Barozzi; A R Di Biase; F Balli; F Cucci; R A Weiss; C Boshoff; G Torelli
Journal:  Br J Cancer       Date:  2000-02       Impact factor: 7.640

8.  Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

Authors:  Nazzarena Labo; Wendell Miley; Vickie Marshall; William Gillette; Dominic Esposito; Matthew Bess; Alexandra Turano; Thomas Uldrick; Mark N Polizzotto; Kathleen M Wyvill; Rachel Bagni; Robert Yarchoan; Denise Whitby
Journal:  PLoS Pathog       Date:  2014-03-27       Impact factor: 6.823

9.  Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: a nested case-control study.

Authors:  Katie Wakeham; W Thomas Johnston; Angela Nalwoga; Emily L Webb; Billy N Mayanja; Wendell Miley; Alison M Elliott; Denise Whitby; Robert Newton
Journal:  Int J Cancer       Date:  2014-11-28       Impact factor: 7.396

  9 in total
  6 in total

1.  Risk Factors for Kaposi's Sarcoma-Associated Herpesvirus DNA in Blood and in Saliva in Rural Uganda.

Authors:  Angela Nalwoga; Marjorie Nakibuule; Vickie Marshall; Wendell Miley; Nazzarena Labo; Stephen Cose; Denise Whitby; Robert Newton
Journal:  Clin Infect Dis       Date:  2020-08-14       Impact factor: 9.079

2.  Kaposi Sarcoma-Associated Herpesvirus Infection and Endemic Burkitt Lymphoma.

Authors:  Peter O Oluoch; Cliff I Oduor; Catherine S Forconi; John M Ong'echa; Christian Münz; Dirk P Dittmer; Jeffrey A Bailey; Ann M Moormann
Journal:  J Infect Dis       Date:  2020-06-16       Impact factor: 5.226

3.  Environmental determinants of Kaposi's sarcoma-associated herpesvirus (KSHV) transmission in rural Uganda (ENDKU study): Contributions to research on KSHV infection and reactivation in African children; A longitudinal cohort study.

Authors:  Katherine R Sabourin; Angela Nalwoga; Denise Whitby; Robert Newton; Rosemary Rochford
Journal:  Cancer Epidemiol       Date:  2022-04-02       Impact factor: 2.890

4.  Longitudinal quantification of adenovirus neutralizing responses in Zambian mother-infant pairs: Impact of HIV-1 infection and its treatment.

Authors:  Sara R Privatt; Brianna L Bullard; Eric A Weaver; Charles Wood; John T West
Journal:  Vaccine       Date:  2019-08-01       Impact factor: 3.641

5.  Variation in KSHV prevalence between geographically proximate locations in Uganda.

Authors:  Angela Nalwoga; Emily L Webb; Claudios Muserere; Belinda Chihota; Wendell Miley; Nazzarena Labo; Alison Elliott; Stephen Cose; Denise Whitby; Robert Newton
Journal:  Infect Agent Cancer       Date:  2020-07-23       Impact factor: 2.965

6.  Malaria Is Associated With Kaposi Sarcoma-Associated Herpesvirus Seroconversion in a Cohort of Western Kenyan Children.

Authors:  Katherine R Sabourin; Ibrahim Daud; Sidney Ogolla; Nazzarena Labo; Wendell Miley; Molly Lamb; Robert Newton; Denise Whitby; Rosemary Rochford
Journal:  J Infect Dis       Date:  2021-07-15       Impact factor: 5.226

  6 in total

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