Naleen Raj Bhandari1, Niranjan Kathe1, Corey Hayes2, Nalin Payakachat3. 1. Division of Pharmaceutical Evaluation and Policy, University of Arkansas for Medical Sciences, Little Rock, AR, USA. 2. Division of Pharmaceutical Evaluation and Policy, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Psychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA. 3. Division of Pharmaceutical Evaluation and Policy, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address: npayakachat@uams.edu.
Abstract
BACKGROUND: The SF-12v2 has been validated in general population and other conditions but the evidence is limited in Americans with cancer. OBJECTIVE: To assess reliability and validity of SF-12v2 among adults with self-reported cancer using the Medical Expenditure Panel Survey (MEPS). METHODS: Self-reported cancer participants (SCPs) were identified from 2003 MEPS. SF-12v2 was administered as part of self-administered questionnaires. Physical (PCS12) and mental (MCS12) component scores of SF-12v2 were evaluated for reliability (internal consistency, test-retest) and validity (convergent, discriminant, predictive, concurrent). RESULTS: 420 SCPs were identified with average age of 59.3 years (SE = 0.9). 10.7% had multiple cancers (>1) and 52% had at least one other chronic condition (OCC). Average PCS12 and MCS12 were 45.09 (SE = 0.5) and 50.75 (SE = 0.5). PCS12 and MCS12 demonstrated high internal consistency (αPCS12 = 0.89; αMCS12 = 0.88), acceptable test-retest reliability (ICCPCS12 = 0.82; ICCMCS12 = 0.73), strongly correlated with most of the expected EQ-5D domains (r = 0.51-0.71), and demonstrated strong convergent validity on perceived health (r = 0.61) and perceived mental health (r = 0.52). PCS12 and MCS12 were able to discriminate between groups with and without physical/cognitive limitations. Only PCS12 was negatively correlated with number of OCCs. CONCLUSION: The SF-12v2 is a reliable and valid instrument to quantify health-related quality of life among adults with self-reported cancer.
BACKGROUND: The SF-12v2 has been validated in general population and other conditions but the evidence is limited in Americans with cancer. OBJECTIVE: To assess reliability and validity of SF-12v2 among adults with self-reported cancer using the Medical Expenditure Panel Survey (MEPS). METHODS: Self-reported cancerparticipants (SCPs) were identified from 2003 MEPS. SF-12v2 was administered as part of self-administered questionnaires. Physical (PCS12) and mental (MCS12) component scores of SF-12v2 were evaluated for reliability (internal consistency, test-retest) and validity (convergent, discriminant, predictive, concurrent). RESULTS: 420 SCPs were identified with average age of 59.3 years (SE = 0.9). 10.7% had multiple cancers (>1) and 52% had at least one other chronic condition (OCC). Average PCS12 and MCS12 were 45.09 (SE = 0.5) and 50.75 (SE = 0.5). PCS12 and MCS12 demonstrated high internal consistency (αPCS12 = 0.89; αMCS12 = 0.88), acceptable test-retest reliability (ICCPCS12 = 0.82; ICCMCS12 = 0.73), strongly correlated with most of the expected EQ-5D domains (r = 0.51-0.71), and demonstrated strong convergent validity on perceived health (r = 0.61) and perceived mental health (r = 0.52). PCS12 and MCS12 were able to discriminate between groups with and without physical/cognitive limitations. Only PCS12 was negatively correlated with number of OCCs. CONCLUSION: The SF-12v2 is a reliable and valid instrument to quantify health-related quality of life among adults with self-reported cancer.
Authors: Victor Okunrintemi; Javier Valero-Elizondo; Erin D Michos; Joseph A Salami; Oluseye Ogunmoroti; Chukwuemeka Osondu; Martin Tibuakuu; Eve-Marie Benson; Timothy M Pawlik; Michael J Blaha; Khurram Nasir Journal: J Gen Intern Med Date: 2019-09-05 Impact factor: 5.128
Authors: Julia R May; Nancy C Jao; Kristen McCarter; Elizabeth Klass; Timothy Pearman; Frank Leone; Robert A Schnoll; Brian Hitsman Journal: Oncol Nurs Forum Date: 2021-01-04 Impact factor: 2.172
Authors: Mohsen Bazargan; James L Smith; Paul Robinson; John Uyanne; Ruqayyah Abdulrahoof; Chika Chuku; Shervin Assari Journal: Int J Environ Res Public Health Date: 2019-05-17 Impact factor: 3.390
Authors: Caroline W Cohen; Kevin R Fontaine; Rebecca C Arend; Taraneh Soleymani; Barbara A Gower Journal: Nutrients Date: 2018-08-30 Impact factor: 5.717