| Literature DB >> 29366605 |
Patricia Sieber1, Matthias Platzer2, Stefan Schuster3.
Abstract
The term open reading frame (ORF) is of central importance to gene finding. Surprisingly, at least three definitions are in use. We discuss several molecular biological and bioinformatics aspects, and we recommend using the definition in which an ORF is bounded by stop codons.Keywords: definition; gene finding; open reading frame; stop codon
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Year: 2018 PMID: 29366605 DOI: 10.1016/j.tig.2017.12.009
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639