Literature DB >> 29366605

The Definition of Open Reading Frame Revisited.

Patricia Sieber1, Matthias Platzer2, Stefan Schuster3.   

Abstract

The term open reading frame (ORF) is of central importance to gene finding. Surprisingly, at least three definitions are in use. We discuss several molecular biological and bioinformatics aspects, and we recommend using the definition in which an ORF is bounded by stop codons.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Keywords:  definition; gene finding; open reading frame; stop codon

Mesh:

Substances:

Year:  2018        PMID: 29366605     DOI: 10.1016/j.tig.2017.12.009

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  8 in total

1.  Accurate detection of short and long active ORFs using Ribo-seq data.

Authors:  Saket Choudhary; Wenzheng Li; Andrew D Smith
Journal:  Bioinformatics       Date:  2020-04-01       Impact factor: 6.937

Review 2.  Functional Micropeptides Encoded by Long Non-Coding RNAs: A Comprehensive Review.

Authors:  Jianfeng Pan; Ruijun Wang; Fangzheng Shang; Rong Ma; Youjun Rong; Yanjun Zhang
Journal:  Front Mol Biosci       Date:  2022-06-13

3.  Turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations.

Authors:  Éléonore Durand; Isabelle Gagnon-Arsenault; Johan Hallin; Isabelle Hatin; Alexandre K Dubé; Lou Nielly-Thibault; Olivier Namy; Christian R Landry
Journal:  Genome Res       Date:  2019-05-31       Impact factor: 9.043

4.  geneRFinder: gene finding in distinct metagenomic data complexities.

Authors:  Raíssa Silva; Kleber Padovani; Fabiana Góes; Ronnie Alves
Journal:  BMC Bioinformatics       Date:  2021-02-25       Impact factor: 3.169

5.  Characterization and complexity of transcriptome in Gymnocypris przewalskii using single-molecule long-read sequencing and RNA-seq.

Authors:  Xindan Li; Jinming Wu; Xinping Xiao; Yifeng Rong; Haile Yang; Junyi Li; Qiong Zhou; Weiguo Zhou; Jianquan Shi; Hongfang Qi; Hao Du
Journal:  DNA Res       Date:  2021-06-25       Impact factor: 4.458

Review 6.  Microproteins in skeletal muscle: hidden keys in muscle physiology.

Authors:  Bernardo Bonilauri; Bruno Dallagiovanna
Journal:  J Cachexia Sarcopenia Muscle       Date:  2021-11-30       Impact factor: 12.910

7.  Unexpected predicted length variation for the coding sequence of the sleep related gene, BHLHE41 in gorilla amidst strong purifying selection across mammals.

Authors:  Krishna Unadkat; Justen B Whittall
Journal:  PLoS One       Date:  2020-04-14       Impact factor: 3.240

Review 8.  Understanding small ORF diversity through a comprehensive transcription feature classification.

Authors:  Diego Guerra-Almeida; Diogo Antonio Tschoeke; Rodrigo Nunes-da-Fonseca
Journal:  DNA Res       Date:  2021-09-13       Impact factor: 4.477

  8 in total

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