Literature DB >> 29365422

[Consensus on clinical diagnosis, treatment and pedigree management of hereditary colorectal cancer in China].

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Abstract

Hereditary colorectal cancer can be divded into two categories based on the presence or absence of polyps. The first category is characterized by the development of polyposis, which includes familial adenomatous polyposis (FAP); The second category is nonpolyposis colorectal cancer, which is represented by Lynch syndrome. "Consensus on clinical diagnosis, treatment and pedigree management of hereditary colorectal cancer in China" developed by the Genetics Group of the Committee of Colorectal Cancer, Chinese Anti-cancer Association, is composed of three sections, including hereditary nonpolyposis syndrome, polyposis syndrome as well as genetic evaluation of hereditary colorectal cancer. The consensus aims to provide recommendations on management of the respective hereditary syndromes in terms of definition, clinical and pathological features, diagnostic standards, treatment, and follow-ups. In addition to describing diagnostic and treatment strategies, prophylactic treatment as well as genetic screening and pedigree monitoring is highly recommended. Through the establishment of this expert consensus, we hope to promote better understanding of hereditary colorectal cancer for clinicians and encourage standardized treatment through multidisciplinery approaches, eventually improving clinical treatment and pedigree management of hereditary colorectal cancer in China.

Entities:  

Keywords:  Familial adenomatous polyposis; Genetic screening; Hereditary colorectal cancer; Lynch syndrome

Mesh:

Year:  2018        PMID: 29365422     DOI: 10.3760/cma.j.issn.0253-3766.2018.01.013

Source DB:  PubMed          Journal:  Zhonghua Zhong Liu Za Zhi        ISSN: 0253-3766


  2 in total

1.  Mutational Analysis of a Familial Adenomatous Polyposis Pedigree with Bile Duct Polyp Phenotype.

Authors:  Li-Jun Xie; Dan-Dan Ruan; Jian-Hui Zhang; Yi Li; Li Chen; Mao-Lin Yan; Ming-Dian Yu; Jie-Wei Luo; Hui-Zhen Zhang
Journal:  Can J Gastroenterol Hepatol       Date:  2021-04-12

Review 2.  Importance of early detection of juvenile polyposis syndrome: A case report and literature review.

Authors:  Na Shen; Xiong Wang; Yanjun Lu; Fang Xiao; Juan Xiao
Journal:  Medicine (Baltimore)       Date:  2020-12-11       Impact factor: 1.817

  2 in total

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