| Literature DB >> 29363069 |
Sabrina Krautbauer1, Gerhard Liebisch2.
Abstract
Besides their role as lipid solubilizers, bile acids (BAs) are increasingly appreciated as bioactive molecules. They bind to G-protein-coupled receptors and nuclear hormone receptors. So they control their own metabolism and act on lipid and energy metabolism. Here we describe a simple, accurate, and fast liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of BAs in human plasma/serum.Entities:
Keywords: Bile acids; Electrospray ionization; Internal standards; Isomer separation; Liquid chromatography; Method; Quantification; Tandem mass spectrometry
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Year: 2018 PMID: 29363069 DOI: 10.1007/978-1-4939-7592-1_8
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745