Literature DB >> 29360929

ST Spot Detector: a web-based application for automatic spot and tissue detection for spatial Transcriptomics image datasets.

Kim Wong1, José Fernández Navarro1, Ludvig Bergenstråhle1, Patrik L Ståhl1, Joakim Lundeberg1.   

Abstract

Motiviation: Spatial Transcriptomics (ST) is a method which combines high resolution tissue imaging with high troughput transcriptome sequencing data. This data must be aligned with the images for correct visualization, a process that involves several manual steps.
Results: Here we present ST Spot Detector, a web tool that automates and facilitates this alignment through a user friendly interface. Contact: jose.fernandez.navarro@scilifelab.se. Supplementary information: Supplementary data are available at Bioinformatics online.

Mesh:

Year:  2018        PMID: 29360929     DOI: 10.1093/bioinformatics/bty030

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  10 in total

1.  Identification of early neurodegenerative pathways in progressive multiple sclerosis.

Authors:  Max Kaufmann; Anna-Lena Schaupp; Rosa Sun; Fabian Coscia; Calliope A Dendrou; Adrian Cortes; Gurman Kaur; Hayley G Evans; Annelie Mollbrink; José Fernández Navarro; Jana K Sonner; Christina Mayer; Gabriele C DeLuca; Joakim Lundeberg; Paul M Matthews; Kathrine E Attfield; Manuel A Friese; Matthias Mann; Lars Fugger
Journal:  Nat Neurosci       Date:  2022-06-20       Impact factor: 28.771

2.  Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma.

Authors:  Andrew L Ji; Adam J Rubin; Kim Thrane; Sizun Jiang; David L Reynolds; Robin M Meyers; Margaret G Guo; Benson M George; Annelie Mollbrink; Joseph Bergenstråhle; Ludvig Larsson; Yunhao Bai; Bokai Zhu; Aparna Bhaduri; Jordan M Meyers; Xavier Rovira-Clavé; S Tyler Hollmig; Sumaira Z Aasi; Garry P Nolan; Joakim Lundeberg; Paul A Khavari
Journal:  Cell       Date:  2020-06-23       Impact factor: 41.582

3.  The spatial RNA integrity number assay for in situ evaluation of transcriptome quality.

Authors:  Linda Kvastad; Konstantin Carlberg; Ludvig Larsson; Eva Gracia Villacampa; Alexander Stuckey; Linnea Stenbeck; Annelie Mollbrink; Margherita Zamboni; Jens Peter Magnusson; Elisa Basmaci; Alia Shamikh; Gabriela Prochazka; Anna-Lena Schaupp; Åke Borg; Lars Fugger; Monica Nistér; Joakim Lundeberg
Journal:  Commun Biol       Date:  2021-01-08

4.  Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis.

Authors:  Max Kaufmann; Hayley Evans; Anna-Lena Schaupp; Jan Broder Engler; Gurman Kaur; Anne Willing; Nina Kursawe; Charlotte Schubert; Kathrine E Attfield; Lars Fugger; Manuel A Friese
Journal:  Med (N Y)       Date:  2021-03-12

Review 5.  Single-Cell Transcriptomics: Current Methods and Challenges in Data Acquisition and Analysis.

Authors:  Asif Adil; Vijay Kumar; Arif Tasleem Jan; Mohammed Asger
Journal:  Front Neurosci       Date:  2021-04-22       Impact factor: 4.677

6.  Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver.

Authors:  Sami Saarenpää; Ludvig Larsson; Noémi Van Hul; Franziska Hildebrandt; Alma Andersson; Sachie Kanatani; Jan Masek; Ewa Ellis; Antonio Barragan; Annelie Mollbrink; Emma R Andersson; Joakim Lundeberg; Johan Ankarklev
Journal:  Nat Commun       Date:  2021-12-02       Impact factor: 14.919

7.  SM-Omics is an automated platform for high-throughput spatial multi-omics.

Authors:  S Vickovic; B Lötstedt; J Klughammer; S Mages; Å Segerstolpe; O Rozenblatt-Rosen; A Regev
Journal:  Nat Commun       Date:  2022-02-10       Impact factor: 14.919

8.  Spatially Resolved Transcriptomes of Mammalian Kidneys Illustrate the Molecular Complexity and Interactions of Functional Nephron Segments.

Authors:  Arti M Raghubar; Duy T Pham; Xiao Tan; Laura F Grice; Joanna Crawford; Pui Yeng Lam; Stacey B Andersen; Sohye Yoon; Siok Min Teoh; Nicholas A Matigian; Anne Stewart; Leo Francis; Monica S Y Ng; Helen G Healy; Alexander N Combes; Andrew J Kassianos; Quan Nguyen; Andrew J Mallett
Journal:  Front Med (Lausanne)       Date:  2022-07-07

Review 9.  Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment.

Authors:  Kaiyue Wu; Kangjia Lin; Xiaoyan Li; Xiangliang Yuan; Peiqing Xu; Peihua Ni; Dakang Xu
Journal:  Front Immunol       Date:  2020-08-04       Impact factor: 7.561

10.  Integrating Spatial Transcriptomics and Single-Cell RNA-seq Reveals the Gene Expression Profling of the Human Embryonic Liver.

Authors:  Xianliang Hou; Yane Yang; Ping Li; Zhipeng Zeng; Wenlong Hu; Ruilian Zhe; Xinqiong Liu; Donge Tang; Minglin Ou; Yong Dai
Journal:  Front Cell Dev Biol       Date:  2021-05-20
  10 in total

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