Literature DB >> 2935814

[Therapeutic prospects of new fluoroquinolones].

A Bryskier, J F Chantot, P Veyssier.   

Abstract

Fluoroquinolones are new synthetic derivatives with a broad spectrum and a potent antibacterial activity this permits to assimilate these molecules as antibiotics. These compounds are characterized by a quinoline or a naphthyridine nucleus with a fluorine atom in position 6 and a piperazine or a pyrrole nucleus in position 7. The combination of their antibacterial properties and the good absorption and tissue distribution allows their use in the treatment of the main infections caused by sensitive strains. The clinical and biological tolerance of these drugs are usually excellent.

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Year:  1985        PMID: 2935814

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  1 in total

1.  Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis.

Authors:  J P Stahl; J Croize; M A Lefèbvre; J P Bru; A Guyot; D Leduc; J B Fourtillan; M Micoud
Journal:  Infection       Date:  1986       Impact factor: 3.553

  1 in total

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