Literature DB >> 29355705

A brief history of modern aging research.

Kayvan Zainabadi1.   

Abstract

Over the last few decades, aging research has emerged as a vibrant area of rigorous scientific study. With its humble beginnings in yeast and worms, the field has progressed so dramatically that scientists are now able to extend the lifespan of mice with the use of small molecule drugs. However, it was not too long ago that answering the more basic question, whether aging was amenable to scientific study, was itself a topic of contentious debate. To begin to understand how a field that was initially thought of as pseudoscience has come so far, it is instructive to understand its roots in both theory and practice.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29355705     DOI: 10.1016/j.exger.2018.01.018

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN: 0531-5565            Impact factor:   4.032


  4 in total

1.  Drug synergy as a strategy for compression of morbidity in a Caenorhabditis elegans model of Alzheimer's disease.

Authors:  Emelyne Teo; Sheng Fong; Nicholas Tolwinski; Jan Gruber
Journal:  Geroscience       Date:  2020-02-22       Impact factor: 7.713

2.  Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion.

Authors:  Yasmine J Liu; Georges E Janssens; Rebecca L McIntyre; Marte Molenaars; Rashmi Kamble; Arwen W Gao; Aldo Jongejan; Michel van Weeghel; Alyson W MacInnes; Riekelt H Houtkooper
Journal:  PLoS Genet       Date:  2019-03-07       Impact factor: 5.917

3.  Construction of Molecular Subtype and Prognosis Prediction Model of Osteosarcoma Based on Aging-Related Genes.

Authors:  Chunli Dong; Yindi Sun; Ying Zhang; Bianni Qin; Tao Lei
Journal:  J Oncol       Date:  2022-09-16       Impact factor: 4.501

4.  The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description.

Authors:  Henne Holstege; Nina Beker; Tjitske Dijkstra; Karlijn Pieterse; Elizabeth Wemmenhove; Kimja Schouten; Linette Thiessens; Debbie Horsten; Sterre Rechtuijt; Sietske Sikkes; Frans W A van Poppel; Hanne Meijers-Heijboer; Marc Hulsman; Philip Scheltens
Journal:  Eur J Epidemiol       Date:  2018-10-25       Impact factor: 8.082

  4 in total

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