Literature DB >> 29355651

Direct and indirect health economic impact of hypoglycaemia in a global population of patients with insulin-treated diabetes.

Ronnie Aronson1, Gagik Galstyan2, Margalit Goldfracht3, Saud Al Sifri4, Lisa Elliott5, Kamlesh Khunti6.   

Abstract

AIMS: The Hypoglycaemia Assessment Tool (HAT) study investigated the health economic impact of hypoglycaemic events in 24 countries, including countries without previously published data on hypoglycaemia.
METHODS: Self-assessment questionnaires and patient diaries (4-week prospective period) were completed by adults with type 1 (T1D) or type 2 diabetes (T2D) treated with insulin for more than 12 months (N = 27,585).
RESULTS: Direct economic impacts of hypoglycaemia during the 4-week prospective period, included increased blood glucose monitoring (reported by 69.7% [T1D] and 60.9% [T2D] of patients), hospitalisation (T1D 2.1%; T2D 3.4% of patients) and medical contact (clinic or telephone; T1D 3.8%; T2D 6.8% of patients). Regional variation in medical contact and hospitalisation was found, with the highest usage in Russia (T1D 17.1%; T2D 17.3%), and Latin America (T1D 5.2%; T2D 6.8%) respectively. Indirect economic impacts following hypoglycaemia included loss of productivity due to absence from work or study; 3.9% (T1D) and 6.2% (T2D) of patients. Regional differences in work productivity were noted among patients with T2D, with a low prevalence in Northern Europe and Canada (0.9%) and high in Southeast Asia (14.6%).
CONCLUSIONS: This study shows that hypoglycaemia has a significant but variable impact on the economics of diabetes healthcare globally.
Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Diabetes; Hypoglycaemia; Insulin; Medical economics; Type 1 diabetes; Type 2 diabetes

Mesh:

Substances:

Year:  2018        PMID: 29355651     DOI: 10.1016/j.diabres.2018.01.007

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  9 in total

1.  Iatrogenic hypoglycemia-related hospital admissions identified through databases: economic burden and causes.

Authors:  Tiphaine Richard; Romane Issa; Emmanuel Andres; Bénédicte Gourieux; Nathalie Jeandidier; Bruno Michel
Journal:  Int J Clin Pharm       Date:  2019-07-23

2.  SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants With Type 1 Diabetes.

Authors:  Schafer C Boeder; Justin M Gregory; Erin R Giovannetti; Jeremy H Pettus
Journal:  Diabetes       Date:  2022-03-01       Impact factor: 9.461

3.  Flash Continuous Glucose Monitoring: A Summary Review of Recent Real-World Evidence.

Authors:  Clifford J Bailey; James R Gavin
Journal:  Clin Diabetes       Date:  2021-01

Review 4.  Inhibitory activities of grape bioactive compounds against enzymes linked with human diseases.

Authors:  Vagish Dwibedi; Sahil Jain; Divya Singhal; Anuradha Mittal; Santosh Kumar Rath; Sanjai Saxena
Journal:  Appl Microbiol Biotechnol       Date:  2022-02-02       Impact factor: 4.813

5.  Sotagliflozin Added to Optimized Insulin Therapy Leads to Lower Rates of Clinically Relevant Hypoglycemic Events at Any HbA1c at 52 Weeks in Adults with Type 1 Diabetes.

Authors:  Thomas Danne; Jeremy Pettus; Andrea Giaccari; Bertrand Cariou; Helena Rodbard; Stuart A Weinzimer; Mireille Bonnemaire; Sangeeta Sawhney; John Stewart; Stella Wang; Rita de Cassia Castro; Satish K Garg
Journal:  Diabetes Technol Ther       Date:  2019-09       Impact factor: 6.118

Review 6.  The consequences of hypoglycaemia.

Authors:  Stephanie A Amiel
Journal:  Diabetologia       Date:  2021-02-07       Impact factor: 10.122

Review 7.  Clinical Use of Insulin Glargine 300 U/mL in Adults with Type 2 Diabetes: Hypothetical Case Studies.

Authors:  Stewart B Harris; Erika B Parente; Janaka Karalliedde
Journal:  Diabetes Ther       Date:  2022-03-30       Impact factor: 3.595

Review 8.  Expert Panel Guidance and Narrative Review of Treatment Simplification of Complex Insulin Regimens to Improve Outcomes in Type 2 Diabetes.

Authors:  Edward B Jude; Maciej T Malecki; Ricardo Gomez Huelgas; Martin Prazny; Frank Snoek; Tsvetalina Tankova; Dario Giugliano; Kamlesh Khunti
Journal:  Diabetes Ther       Date:  2022-03-11       Impact factor: 2.945

9.  The SAGE study: Global observational analysis of glycaemic control, hypoglycaemia and diabetes management in T1DM.

Authors:  Eric Renard; Hiroshi Ikegami; André Gustavo Daher Vianna; Paolo Pozzilli; Sandrine Brette; Zsolt Bosnyak; Felipe Lauand; Anne Peters; Valerie Pilorget; Dubravka Jurišić-Eržen; Jothydev Kesavadev; Jochen Seufert; Emma G Wilmot
Journal:  Diabetes Metab Res Rev       Date:  2021-03-02       Impact factor: 4.876

  9 in total

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