Duosheng Jiang1, Yingchun Zhang1, Xiaolan Wu2, Yanming Wang2, Qiangfang Fan2, Song Wu3. 1. Department of TCM, Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China. 2. Department of Gynecology, Huanggang TCM Hospital. 3. Hubei University of CM/ Hubei Collaborative Innovation Center of Acupuncture for Prevention.
Abstract
OBJECTIVE: To compare the efficacy differences between ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula and Bushen Huoxue formula alone on patients with decreased ovarian reserve function. METHODS:Fifty patients of decreased ovarian reserve function were randomly divided into an observation group and a control group, 25 cases in each one. The patients in the observation group were treated with ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula; the moxibustion was given for 1.5 h, once every seven days, and no treatment was given during menstrual period. The patients in the control group were treated with Bushen Huoxue formula. One-month treatment was taken as one treatment course, and totally three courses were given. The change of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), anti-mullerian hormone (AMH), antral follicle count (AFC), peak systolic velocity (PSV), resistance index (RI) were observed before and after treatment in the two groups. RESULTS: After treatment, the FSH, FSH/LH and RI were significantly lowered, but the E2, AFC, PSV were significantly increased in the two groups (all P<0.05); the FSH, FSH/LH and E2 in the observation group were lower and AFC was higher than those in the control group (all P<0.05). CONCLUSION: The ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula are superior to Bushen Huoxue formula alone in improving ovarian reserve function.
RCT Entities:
OBJECTIVE: To compare the efficacy differences between ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula and Bushen Huoxue formula alone on patients with decreased ovarian reserve function. METHODS: Fifty patients of decreased ovarian reserve function were randomly divided into an observation group and a control group, 25 cases in each one. The patients in the observation group were treated with ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula; the moxibustion was given for 1.5 h, once every seven days, and no treatment was given during menstrual period. The patients in the control group were treated with Bushen Huoxue formula. One-month treatment was taken as one treatment course, and totally three courses were given. The change of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), anti-mullerian hormone (AMH), antral follicle count (AFC), peak systolic velocity (PSV), resistance index (RI) were observed before and after treatment in the two groups. RESULTS: After treatment, the FSH, FSH/LH and RI were significantly lowered, but the E2, AFC, PSV were significantly increased in the two groups (all P<0.05); the FSH, FSH/LH and E2 in the observation group were lower and AFC was higher than those in the control group (all P<0.05). CONCLUSION: The ginger-separated moxibustion at Baliao points combined with Bushen Huoxue formula are superior to Bushen Huoxue formula alone in improving ovarian reserve function.