Literature DB >> 29353666

Erratum to: Hafeez S, McDonald F, Lalondrelle S, et al. Clinical outcomes of image guided adaptive hypofractionated weekly radiation therapy for bladder cancer in patients unsuitable for radical treatment. Int J Radiat Oncol Biol Phys 2017;98:115-122.

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Year:  2018        PMID: 29353666      PMCID: PMC6859496          DOI: 10.1016/j.ijrobp.2017.11.005

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


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The authors wish to bring to the readers' attention typographical error identified in Supplementary Table 2 with the online version of the article showing the dose constraints guidance used for 3D conformal planning for total prescription dose of 36Gy in 6 fractions (1). The content of the columns for other bowel were inadvertently moved in formatting. This was not recognized by the authors at the time of manuscript review. The corrected Supplementary Table 2 is as below. We apologize for any inconvenience. Dose constraints guidance used for 3D conformal planning for total prescription dose of 36Gy in 6 fractions Proposed constraints are based on total prescription dose of 36Gy prescribed to 100% at the International Commission on Radiation Units and Measurements reference point. In those with advanced disease or limited performance status 30Gy in 5 fractions was considered (three patients planned to 30Gy in 5 fractions). Dose constraints were derived from previously recruited phase III studies (CHHIP and BC2001) using linear quadratic model assuming α/β of 10 for tumor control and 3 for normal tissue 2, 3, 4, 5. Organs at risk were contoured as solid structures by defining their outer wall on CT0. Other bowel constraints were specified only for the small plan and medium plan as it was expected that the large plan would exceed above constraints given the position of bowel on the planning CT scan is not reflective of true bowel position at treatment delivery when large plan would be selected for treatment.
Supplementary Table 2

Dose constraints guidance used for 3D conformal planning for total prescription dose of 36Gy in 6 fractions

OrganConstraint
Rectum(including anus)17Gy80%
28Gy60%
33Gy50%
36Gy30%
Femoral heads28Gy50%
Other bowel(including small and large bowel as a single structure)optimalmandatory
V25139cc208cc
V28122cc183cc
V31105cc157cc
V3384cc126cc
V3626cc39cc

Proposed constraints are based on total prescription dose of 36Gy prescribed to 100% at the International Commission on Radiation Units and Measurements reference point. In those with advanced disease or limited performance status 30Gy in 5 fractions was considered (three patients planned to 30Gy in 5 fractions). Dose constraints were derived from previously recruited phase III studies (CHHIP and BC2001) using linear quadratic model assuming α/β of 10 for tumor control and 3 for normal tissue 2, 3, 4, 5. Organs at risk were contoured as solid structures by defining their outer wall on CT0. Other bowel constraints were specified only for the small plan and medium plan as it was expected that the large plan would exceed above constraints given the position of bowel on the planning CT scan is not reflective of true bowel position at treatment delivery when large plan would be selected for treatment.

  5 in total

1.  Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial.

Authors:  David Dearnaley; Isabel Syndikus; Georges Sumo; Margaret Bidmead; David Bloomfield; Catharine Clark; Annie Gao; Shama Hassan; Alan Horwich; Robert Huddart; Vincent Khoo; Peter Kirkbride; Helen Mayles; Philip Mayles; Olivia Naismith; Chris Parker; Helen Patterson; Martin Russell; Christopher Scrase; Chris South; John Staffurth; Emma Hall
Journal:  Lancet Oncol       Date:  2011-12-12       Impact factor: 41.316

2.  Radical radiotherapy for invasive bladder cancer: What dose and fractionation schedule to choose?

Authors:  Floris J Pos; Guus Hart; Christoph Schneider; Peter Sminia
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-01-10       Impact factor: 7.038

3.  Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer.

Authors:  Nicholas D James; Syed A Hussain; Emma Hall; Peter Jenkins; Jean Tremlett; Christine Rawlings; Malcolm Crundwell; Bruce Sizer; Thiagarajan Sreenivasan; Carey Hendron; Rebecca Lewis; Rachel Waters; Robert A Huddart
Journal:  N Engl J Med       Date:  2012-04-19       Impact factor: 91.245

4.  Defining bowel dose volume constraints for bladder radiotherapy treatment planning.

Authors:  F McDonald; R Waters; S Gulliford; E Hall; N James; R A Huddart
Journal:  Clin Oncol (R Coll Radiol)       Date:  2014-11-01       Impact factor: 4.126

5.  Clinical Outcomes of Image Guided Adaptive Hypofractionated Weekly Radiation Therapy for Bladder Cancer in Patients Unsuitable for Radical Treatment.

Authors:  Shaista Hafeez; Fiona McDonald; Susan Lalondrelle; Helen McNair; Karole Warren-Oseni; Kelly Jones; Victoria Harris; Helen Taylor; Vincent Khoo; Karen Thomas; Vibeke Hansen; David Dearnaley; Alan Horwich; Robert Huddart
Journal:  Int J Radiat Oncol Biol Phys       Date:  2017-02-09       Impact factor: 7.038

  5 in total

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