Literature DB >> 2935250

Relationship of structure to anticancer activity and toxicity of the nitrosoureas in animal systems.

T P Johnston, J A Montgomery.   

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Year:  1986        PMID： 2935250

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN： 0361-5960


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  10 in total

1.  A strategy for selective O(6)-alkylguanine-DNA alkyltransferase depletion under hypoxic conditions.

Authors:  Philip G Penketh; Krishnamurthy Shyam; Raymond P Baumann; Kimiko Ishiguro; Eric V Patridge; Rui Zhu; Alan C Sartorelli
Journal:  Chem Biol Drug Des       Date:  2012-05-23       Impact factor: 2.817

2.  Genotoxic and cytotoxic effects of 4-aroyl-1-nitrosohydrazine-carboxamides on O6-alkylguanine-DNA alkyltransferase-positive and -negative human cell lines.

Authors:  C Schell; O Lantermann; W Popp; C Vahrenholz; J Thomale; R Gugova; E Golovinsky; K Norpoth
Journal:  J Cancer Res Clin Oncol       Date:  1994       Impact factor: 4.553

3.  Antitumor activity of semisynthetic derivatives of Aconitum alkaloids.

Authors:  Ainura Chodoeva; Jean-Jacques Bosc; Lydia Lartigue; Jean Guillon; Céline Auzanneau; Pierre Costet; Ashiraly Zurdinov; Christian Jarry; Jacques Robert
Journal:  Invest New Drugs       Date:  2013-06-13       Impact factor: 3.850

4.  Thioredoxin reductase is inhibited by the carbamoylating activity of the anticancer sulfonylhydrazine drug laromustine.

Authors:  Kevin P Rice; Edmund J Klinkerch; Scott A Gerber; Tyler R Schleicher; Tara J Kraus; Christopher M Buros
Journal:  Mol Cell Biochem       Date:  2012-08-05       Impact factor: 3.396

5.  Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine.

Authors:  Abbie M Frederick; Marguerite L Davis; Kevin P Rice
Journal:  Biochem Biophys Res Commun       Date:  2008-11-21       Impact factor: 3.575

6.  Chemical stability of ecomustine, a new antitumor agent in aqueous and biological media as assessed by high-performance liquid chromatography.

Authors:  I el Abed; P Roger; C Gosse; G Atassi; A Gouyette
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

7.  Influence of phosphate and phosphoesters on the decomposition pathway of 1,2-bis(methylsulfonyl)-1-(2-chloroethyhydrazine (90CE), the active anticancer moiety generated by Laromustine, KS119, and KS119W.

Authors:  Philip G Penketh; Krishnamurthy Shyam; Rui Zhu; Raymond P Baumann; Kimiko Ishiguro; Alan C Sartorelli
Journal:  Chem Res Toxicol       Date:  2014-03-24       Impact factor: 3.739

8.  Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.

Authors:  Weidong Ji; Mei Yang; Alexandra Praggastis; Yonghao Li; Huanjiao Jenny Zhou; Yun He; Roxanne Ghazvinian; Dylan J Cincotta; Kevin P Rice; Wang Min
Journal:  PLoS One       Date:  2014-07-28       Impact factor: 3.240

9.  Activity of a new nitrosourea (TCNU) in human lung cancer xenografts.

Authors:  R J Fergusson; L E Anderson; J S Macpherson; P Robins; J F Smyth
Journal:  Br J Cancer       Date:  1988-04       Impact factor: 7.640

10.  Influence of glutathione and glutathione S-transferases on DNA interstrand cross-link formation by 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine, the active anticancer moiety generated by laromustine.

Authors:  Philip G Penketh; Eric Patridge; Krishnamurthy Shyam; Raymond P Baumann; Rui Zhu; Kimiko Ishiguro; Alan C Sartorelli
Journal:  Chem Res Toxicol       Date:  2014-07-17       Impact factor: 3.739
  10 in total

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