Literature DB >> 29352364

[Accidental central venous administation of 0.1 % chlorhexidine mouthwash].

M Ploner1,2, L M Löffel3,4, G Schüpfer3, I Besmer3, C J Konrad3.   

Abstract

Medication errors are frequent and a serious safety concern. Chlorhexidine (CHX) is used daily in healthcare as a disinfectant. Its accidental intravascular injection is scarcely described. Serious complications, such as acute respiratory distress syndrome (ARDS) could be a consequence. We describe a case of central venous administration of 0.1% CHX mouthwash, its potential complications and possibilities of treatment. In contrast to another case report our patient had no detectable adverse side effects. The immediate hemofiltration and cleansing of the i. v. line may have contributed to this favorable outcome.

Entities:  

Keywords:  Acute respiratory distress syndrome; Chlorhexidine; Extracorporeal membrane oxygenation; Hemofiltration; Medication error

Mesh:

Substances:

Year:  2018        PMID: 29352364     DOI: 10.1007/s00101-018-0408-7

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  9 in total

Review 1.  Dialysis and hemoperfusion in poisoning.

Authors:  James F Winchester
Journal:  Adv Ren Replace Ther       Date:  2002-01

2.  The frequency and nature of drug administration error during anaesthesia.

Authors:  C S Webster; A F Merry; L Larsson; K A McGrath; J Weller
Journal:  Anaesth Intensive Care       Date:  2001-10       Impact factor: 1.669

3.  Intravenous chlorhexidine gluconate causing acute respiratory distress syndrome.

Authors:  S Ishigami; S Hase; H Nakashima; H Yamada; H Dohgomori; S Natsugoe; T Aikou
Journal:  J Toxicol Clin Toxicol       Date:  2001

4.  Effectiveness of 0.12% chlorhexidine gluconate oral rinse in reducing prevalence of nosocomial pneumonia in patients undergoing heart surgery.

Authors:  Susan Houston; Paul Hougland; Jacqueline J Anderson; Mark LaRocco; Virginia Kennedy; Layne O Gentry
Journal:  Am J Crit Care       Date:  2002-11       Impact factor: 2.228

Review 5.  Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis.

Authors:  Sonia O Labeau; Katrien Van de Vyver; Nele Brusselaers; Dirk Vogelaers; Stijn I Blot
Journal:  Lancet Infect Dis       Date:  2011-07-26       Impact factor: 25.071

6.  Comparative study on toxic effects induced by oral or intravascular administration of commonly used disinfectants and surfactants in rats.

Authors:  Yuying Xue; Shanshan Zhang; Meng Tang; Ting Zhang; Yiqing Wang; Yoko Hieda; Haruo Takeshita
Journal:  J Appl Toxicol       Date:  2011-03-09       Impact factor: 3.446

Review 7.  Severe adhesive arachnoiditis resulting in progressive paraplegia following obstetric spinal anaesthesia: a case report and review.

Authors:  T Killeen; A Kamat; D Walsh; A Parker; A Aliashkevich
Journal:  Anaesthesia       Date:  2012-10-12       Impact factor: 6.955

Review 8.  Chlorhexidine--pharmacology and clinical applications.

Authors:  K-S Lim; P C A Kam
Journal:  Anaesth Intensive Care       Date:  2008-07       Impact factor: 1.669

9.  Errors in administration of parenteral drugs in intensive care units: multinational prospective study.

Authors:  Andreas Valentin; Maurizia Capuzzo; Bertrand Guidet; Rui Moreno; Barbara Metnitz; Peter Bauer; Philipp Metnitz
Journal:  BMJ       Date:  2009-03-12
  9 in total
  1 in total

1.  A not so rosy picture: accidental intravenous injection of rose-tinted pourable chlorhexidine solution.

Authors:  Neeti Dogra; Devant Goswami; Sumit Kumar
Journal:  Braz J Anesthesiol       Date:  2021-10-08
  1 in total

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