Literature DB >> 29351837

Try Me: Promiscuous Inhibitors Still Allow for Selective Targeted Protein Degradation.

Matthias P Müller1, Daniel Rauh2.   

Abstract

In this issue of Cell Chemical Biology, Bondeson et al. (2018), Burslem et al. (2018), and Huang et al. (2018) systematically characterize proteolysis-targeting chimeras (PROTACs) regarding their specificity and general advantages of targeted proteolysis of cellular proteins and provide interesting insights into possible future developments.
Copyright © 2018 Elsevier Ltd. All rights reserved.

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Year:  2018        PMID: 29351837     DOI: 10.1016/j.chembiol.2018.01.004

Source DB:  PubMed          Journal:  Cell Chem Biol        ISSN: 2451-9448            Impact factor:   8.116


  1 in total

Review 1.  Inducing the Degradation of Disease-Related Proteins Using Heterobifunctional Molecules.

Authors:  Alexandré Delport; Raymond Hewer
Journal:  Molecules       Date:  2019-09-08       Impact factor: 4.411

  1 in total

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