| Literature DB >> 29351512 |
Alexei Verkhratsky1, Maiken Nedergaard1.
Abstract
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.Entities:
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Year: 2018 PMID: 29351512 PMCID: PMC6050349 DOI: 10.1152/physrev.00042.2016
Source DB: PubMed Journal: Physiol Rev ISSN: 0031-9333 Impact factor: 37.312