Literature DB >> 2935142

Genetic and biochemical characterization of phosphofructokinase from Drosophila melanogaster.

L R Munneke, G E Collier.   

Abstract

Phosphofructokinase (PFK;EC 2.7.1.11) activity in Drosophila melanogaster is controlled by a single dosage-sensitive region of the genome between 45F and 47E of chromosome IIR. Only a single form of PFK was detected electrophoretically in both adults and larvae. Nearly 90% of the PFK activity in adults is localized to the thorax. Purification of the enzyme was hampered by the extreme lability of Drosophila PFK; however, a 36-fold partial purification was achieved.

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Year:  1985        PMID: 2935142     DOI: 10.1007/bf00499933

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  20 in total

1.  The activities of phosphorylase, hexokinase, phosphofructokinase, lactate dehydrogenase and the glycerol 3-phosphate dehydrogenases in muscles from vertebrates and invertebrates.

Authors:  B Crabtree; E A Newsholme
Journal:  Biochem J       Date:  1972-01       Impact factor: 3.857

2.  Allosteric nature of thermostable phosphofructokinase from an extreme thermophilic bacterium.

Authors:  M Yoshida
Journal:  Biochemistry       Date:  1972-03-14       Impact factor: 3.162

3.  Purification and properties of phosphofructokinase from yeast.

Authors:  T J Lindell; E Stellwagen
Journal:  J Biol Chem       Date:  1968-03-10       Impact factor: 5.157

4.  Crystallization and properties of rabbit skeletal muscle phosphofructokinase.

Authors:  A Parmeggiani; J H Luft; D S Love; E G Krebs
Journal:  J Biol Chem       Date:  1966-10-25       Impact factor: 5.157

5.  Rat liver phosphofructokinase isozymes.

Authors:  G A Dunaway; G Weber
Journal:  Arch Biochem Biophys       Date:  1974-06       Impact factor: 4.013

6.  Regulation of enzyme activities in Drosophila. II. Characterization of enzyme responses in aneuploid flies.

Authors:  J M Rawls; J C Lucchesi
Journal:  Genet Res       Date:  1974-08       Impact factor: 1.588

7.  Regulation of enzyme activities in Drosophila. I. The detection of regulatory loci by gene dosage responses.

Authors:  J M Rawls; J C Lucchesi
Journal:  Genet Res       Date:  1974-08       Impact factor: 1.588

8.  A comparison of the properties of the phosphofructokinases of the fat body and flight muscle of the adult male desert locust.

Authors:  P R Walker; E Bailey
Journal:  Biochem J       Date:  1969-02       Impact factor: 3.857

9.  Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes.

Authors:  S J O'Brien; R C Gethmann
Journal:  Genetics       Date:  1973-09       Impact factor: 4.562

10.  Localization of a dosage sensitive region for pyruvate kinase in Drosophila melanogaster.

Authors:  K J Rust; G E Collier
Journal:  J Hered       Date:  1985 Jan-Feb       Impact factor: 2.645

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