Literature DB >> 2935125

Abnormal retinal function associated with fenretinide, a synthetic retinoid.

M I Kaiser-Kupfer, G L Peck, R C Caruso, M J Jaffe, J J DiGiovanna, E G Gross.   

Abstract

Five patients with basal cell carcinoma received fenretinide. Two patients while receiving the drug had evidence of abnormal rod photoreceptor function that reversed rapidly on cessation of therapy. We speculate that fenretinide may interfere with the binding of vitamin A to opsin or with the transport of vitamin A.

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Year:  1986        PMID: 2935125     DOI: 10.1001/archopht.1986.01050130079024

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  12 in total

1.  Does use of isotretinoin rule out a career in flying?

Authors:  S P Mollan; M Woodcock; R Siddiqi; J Huntbach; P Good; R A H Scott
Journal:  Br J Ophthalmol       Date:  2006-05-24       Impact factor: 4.638

2.  Visual toxicity of synthetic retinoids.

Authors:  R D Brown; C E Grattan
Journal:  Br J Ophthalmol       Date:  1989-04       Impact factor: 4.638

Review 3.  Adverse effects of retinoids.

Authors:  M David; E Hodak; N J Lowe
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Jul-Aug

4.  Lecithin:retinol acyltransferase is critical for cellular uptake of vitamin A from serum retinol-binding protein.

Authors:  Jaume Amengual; Marcin Golczak; Krzysztof Palczewski; Johannes von Lintig
Journal:  J Biol Chem       Date:  2012-05-27       Impact factor: 5.157

5.  Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study.

Authors:  Vinay K Puduvalli; W K Alfred Yung; Kenneth R Hess; John G Kuhn; Morris D Groves; Victor A Levin; James Zwiebel; Susan M Chang; Timothy F Cloughesy; Larry Junck; Patrick Wen; Frank Lieberman; Charles A Conrad; Mark R Gilbert; Christina A Meyers; Vivien Liu; Minesh P Mehta; M Kelly Nicholas; Michael Prados
Journal:  J Clin Oncol       Date:  2004-11-01       Impact factor: 44.544

6.  Phase II study of fenretinide (N-[4-hydroxyphenyl]retinamide) in advanced breast cancer and melanoma.

Authors:  M R Modiano; W S Dalton; S M Lippman; L Joffe; A R Booth; F L Meyskens
Journal:  Invest New Drugs       Date:  1990-08       Impact factor: 3.850

Review 7.  Fenretinide in Cancer and Neurological Disease: A Two-Face Janus Molecule.

Authors:  Rosa Luisa Potenza; Pietro Lodeserto; Isabella Orienti
Journal:  Int J Mol Sci       Date:  2022-07-04       Impact factor: 6.208

8.  Total rod ERG suppression with high dose compassionate Fenretinide usage.

Authors:  Michael F Marmor; Atul Jain; Darius Moshfeghi
Journal:  Doc Ophthalmol       Date:  2008-06-04       Impact factor: 2.379

Review 9.  Risks and benefits of retinoids in the chemoprevention of cancer.

Authors:  G de Palo; F Formelli
Journal:  Drug Saf       Date:  1995-10       Impact factor: 5.606

10.  The retina rapidly incorporates ingested C20-D₃-vitamin A in a swine model.

Authors:  Doina M Mihai; Hongfeng Jiang; William S Blaner; Alexander Romanov; Ilyas Washington
Journal:  Mol Vis       Date:  2013-07-25       Impact factor: 2.367

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