| Literature DB >> 29348531 |
Zhen-Jie Li1, Hai-Ying Yang2, Jing Li1, Xin Liu1, Lin Ye1, Wei-Song Kong1, Shi-Yun Tang1, Gang Du2, Zhi-Hua Liu1, Min Zhou2, Guang-Yu Yang1,2, Qiu-Fen Hu3, Xue-Mei Li4.
Abstract
Three new isopentylated diphenyl ethers, (1-3), together with two known isopentylated diphenyl ethers derivatives (4 and 5) were isolated from the fermentation products of an endophytic fungus Phomopsis fukushii. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-3 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results showed that compounds 1-3 showed strong activity with diameter of inhibition zone (IZD) of 21.8 ± 2.4 mm, 16.8 ± 2.2 mm, and 15.6 ± 2.0 mm, respectively.Entities:
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Year: 2018 PMID： 29348531 DOI： 10.1038/s41429-017-0006-y
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649