Literature DB >> 2934746

Analgesic properties of enkephalinase inhibitors: animal and human studies.

S Ehrenpreis.   

Abstract

D-phenylalanine, bacitracin and puromycin produce long-lasting, naloxone-reversible analgesia in mice. Analgesic potency parallels potency of these compounds as inhibitors of met-enkephalin degradation by mouse brain enzymes. D-phenylalanine potentiates acupuncture analgesia in mice and humans and has been used to ameliorate a variety of human chronic pain conditions.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2934746

Source DB:  PubMed          Journal:  Prog Clin Biol Res        ISSN： 0361-7742


  2 in total

1.  Nicotinamide Adenine Dinucleotide (NAD+) and Enkephalinase Inhibition (IV1114589NAD) Infusions Significantly Attenuate Psychiatric Burden Sequalae in Substance Use Disorder (SUD) in Fifty Cases.

Authors:  Kenneth Blum; David Han; David Baron; Shan Kazmi; Igor Elman; Luis Llanos Gomez; Marjorie C Gondre-Lewis; Panyotis K Thanos; Eric R Braverman; Rajendra D Badgaiyan
Journal:  Curr Psychiatry Res Rev       Date:  2022-06-21

2.  A Multi-Locus Approach to Treating Fibromyalgia by Boosting Dopaminergic Activity in the Meso-Limbic System of the Brain.

Authors:  Kenneth Blum; Marlene Oscar-Berman; Roger L Waite; Eric R Braverman; Florian Kreuk; Mona Li; Kristina Dushaj; Margaret A Madigan; Mary Hauser; Thomas Simpatico; Debmalya Barh
Journal:  J Genet Syndr Gene Ther       Date:  2014-01-27
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.