| Literature DB >> 2934629 |
C F Menck, J B Cabral-Neto, A Faljoni-Alário, R Alcantara-Gomes.
Abstract
Exposure of lambda phage to triplet acetone, generated via the oxidation of isobutanal by peroxidase, leads to genome lesions. The majority of these lesions are detected as DNA single-strand breaks only under alkaline conditions, and so true breaks do not occur. Also, no sites sensitive to UV-endonuclease from Micrococcus luteus were found in DNA from treated phage. The participation of triplet acetone in the generation of such DNA damage is discussed.Entities:
Mesh：
Substances：
Year: 1986 PMID： 2934629 DOI： 10.1016/0167-8817(86)90003-9
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433