| Literature DB >> 29346163 |
Kevin I Watt1,1,1, Craig A Goodman1,1,1, Troy A Hornberger1, Paul Gregorevic1,1,1.
Abstract
The Hippo signaling pathway regulates the activity of the proteins Yes-associated protein (Yap) and transcriptional co-activator with PDZ-binding motif (Taz) to control tissue growth in many different cell types. Previously, we demonstrated that Yap is a critical regulator of skeletal muscle mass. We hypothesize that alterations in Yap and Taz activity modulate the anabolic adaptations of skeletal muscle to resistance exercise.Entities:
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Year: 2018 PMID: 29346163 PMCID: PMC6319272 DOI: 10.1249/JES.0000000000000142
Source DB: PubMed Journal: Exerc Sport Sci Rev ISSN: 0091-6331 Impact factor: 6.230