Literature DB >> 29344764

O-GlcNAcylation: key regulator of glycolytic pathways.

Zachary A Bacigalupa1, Chaitali H Bhadiadra1, Mauricio J Reginato2.   

Abstract

Elevated O-GlcNAcylation is emerging as a general characteristic of most cancers. Although O-GlcNAcylation can regulate many cell biological pathways, recent evidence suggests that it is a key regulator of metabolic pathways including glycolysis in cancer cells. This review summarizes our current understanding of how O-GlcNAcylation regulates glycolytic pathways and contributes to alterations in cancer cell metabolism.

Entities:  

Keywords:  Cancer; Glycolysis; Metabolism; O-GlcNAc transferase; O-GlcNAcylation

Mesh：

Substances：

Year:  2018        PMID： 29344764      PMCID： PMC9386736          DOI： 10.1007/s10863-018-9742-3

Source DB:  PubMed          Journal:  J Bioenerg Biomembr        ISSN： 0145-479X            Impact factor:   3.853


  124 in total

1.  On respiratory impairment in cancer cells.

Authors:  O WARBURG
Journal:  Science       Date:  1956-08-10       Impact factor: 47.728

2.  Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.

Authors:  Keith Vosseller; Lance Wells; M Daniel Lane; Gerald W Hart
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

3.  Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide beta-N-acetylglucosaminyltransferase.

Authors:  R S Haltiwanger; G D Holt; G W Hart
Journal:  J Biol Chem       Date:  1990-02-15       Impact factor: 5.157

4.  Systematic identification of the protein substrates of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T1/T2/T3 using a human proteome microarray.

Authors:  Zhijue Xu; Xing Li; Shumin Zhou; Wenxian Xie; Jing Wang; Li Cheng; Sheng Wang; Shujuan Guo; Zhaowei Xu; Xin Cao; Menghui Zhang; Biao Yu; Hisashi Narimatsu; Sheng-Ce Tao; Yan Zhang
Journal:  Proteomics       Date:  2017-06       Impact factor: 3.984

Review 5.  Rethinking the Warburg effect with Myc micromanaging glutamine metabolism.

Authors:  Chi V Dang
Journal:  Cancer Res       Date:  2010-01-19       Impact factor: 12.701

6.  Glycosylation of the c-Myc transactivation domain.

Authors:  T Y Chou; C V Dang; G W Hart
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

7.  A nutrient-sensing pathway regulates leptin gene expression in muscle and fat.

Authors:  J Wang; R Liu; M Hawkins; N Barzilai; L Rossetti
Journal:  Nature       Date:  1998-06-18       Impact factor: 49.962

8.  O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth.

Authors:  Xiongjian Rao; Xiaotao Duan; Weimin Mao; Xuexia Li; Zhonghua Li; Qian Li; Zhiguo Zheng; Haimiao Xu; Min Chen; Peng G Wang; Yingjie Wang; Binghui Shen; Wen Yi
Journal:  Nat Commun       Date:  2015-09-24       Impact factor: 14.919

9.  Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Authors:  Zachary T Schug; Barrie Peck; Dylan T Jones; Qifeng Zhang; Shaun Grosskurth; Israt S Alam; Louise M Goodwin; Elizabeth Smethurst; Susan Mason; Karen Blyth; Lynn McGarry; Daniel James; Emma Shanks; Gabriela Kalna; Rebecca E Saunders; Ming Jiang; Michael Howell; Francois Lassailly; May Zaw Thin; Bradley Spencer-Dene; Gordon Stamp; Niels J F van den Broek; Gillian Mackay; Vinay Bulusu; Jurre J Kamphorst; Saverio Tardito; David Strachan; Adrian L Harris; Eric O Aboagye; Susan E Critchlow; Michael J O Wakelam; Almut Schulze; Eyal Gottlieb
Journal:  Cancer Cell       Date:  2015-01-12       Impact factor: 31.743

10.  O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson's disease.

Authors:  Willayat Y Wani; Xiaosen Ouyang; Gloria A Benavides; Matthew Redmann; Stacey S Cofield; John J Shacka; John C Chatham; Victor Darley-Usmar; Jianhua Zhang
Journal:  Mol Brain       Date:  2017-07-19       Impact factor: 4.041
View more
  13 in total

Review 1.  Protein O-GlcNAcylation in cardiovascular diseases.

Authors:  Hui-Fang Wang; Yi-Xuan Wang; Yu-Ping Zhou; Yun-Peng Wei; Yi Yan; Ze-Jian Zhang; Zhi-Cheng Jing
Journal:  Acta Pharmacol Sin       Date:  2022-07-11       Impact factor: 7.169

2.  RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure.

Authors:  Yang Liu; Hongzhao Shi; Yajie Hu; Ruizhi Yao; Peng Liu; Yuying Yang; Shize Li
Journal:  Cell Stress Chaperones       Date:  2022-09-23       Impact factor: 3.827

Review 3.  Posttranslational modifications in diabetes: Mechanisms and functions.

Authors:  Bin Chen; Jianing Zhong; Ang Hu; Haohong Zou
Journal:  Rev Endocr Metab Disord       Date:  2022-06-13       Impact factor: 9.306

4.  O-GlcNAc modification mediates aquaporin 3 to coordinate endometrial cell glycolysis and affects embryo implantation.

Authors:  Hongshuo Zhang; Jia Qi; Jingyuan Pei; Man Zhang; Yuhong Shang; Zhen Li; Yufei Wang; Jinqiu Guo; Kaiqi Sun; Jianhui Fan; Linlin Sui; Yuefei Xu; Li Kong; Ying Kong
Journal:  J Adv Res       Date:  2021-06-30       Impact factor: 12.822

Review 5.  Regulation of cardiac O-GlcNAcylation: More than just nutrient availability.

Authors:  Helen E Collins; John C Chatham
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2020-01-31       Impact factor: 5.187

6.  Apart From Rhoptries, Identification of Toxoplasma gondii's O-GlcNAcylated Proteins Reinforces the Universality of the O-GlcNAcome.

Authors:  Moyira Osny Aquino-Gil; Mattis Kupferschmid; Hosam Shams-Eldin; Jörg Schmidt; Nao Yamakawa; Marlène Mortuaire; Frédéric Krzewinski; Stéphan Hardivillé; Edgar Zenteno; Christian Rolando; Fabrice Bray; Eduardo Pérez Campos; Jean-François Dubremetz; Yobana Perez-Cervera; Ralph T Schwarz; Tony Lefebvre
Journal:  Front Endocrinol (Lausanne)       Date:  2018-08-20       Impact factor: 5.555

Review 7.  O-GlcNAcylation in Hyperglycemic Pregnancies: Impact on Placental Function.

Authors:  Jie Ning; Huixia Yang
Journal:  Front Endocrinol (Lausanne)       Date:  2021-06-01       Impact factor: 5.555

8.  High Fat Activates O-GlcNAcylation and Affects AMPK/ACC Pathway to Regulate Lipid Metabolism.

Authors:  Yuning Pang; Xiang Xu; Xiaojun Xiang; Yongnan Li; Zengqi Zhao; Jiamin Li; Shengnan Gao; Qiangde Liu; Kangsen Mai; Qinghui Ai
Journal:  Nutrients       Date:  2021-05-21       Impact factor: 5.717

Review 9.  Involvement of O-GlcNAcylation in the Skeletal Muscle Physiology and Physiopathology: Focus on Muscle Metabolism.

Authors:  Matthias Lambert; Bruno Bastide; Caroline Cieniewski-Bernard
Journal:  Front Endocrinol (Lausanne)       Date:  2018-10-16       Impact factor: 5.555

Review 10.  Role of O-Linked N-Acetylglucosamine Protein Modification in Cellular (Patho)Physiology.

Authors:  John C Chatham; Jianhua Zhang; Adam R Wende
Journal:  Physiol Rev       Date:  2020-07-30       Impact factor: 37.312
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.