PURPOSE: To report a treatment approach for advanced extrascleral uveal melanoma. METHODS: We performed clinical examination including magnetic resonance imaging, computed tomography, angiography, and histopathologic analysis. CASE: A 49-year-old healthy woman presented with a 7-year history of an enlarging pigmented mass in her right orbit. Malignant melanoma was diagnosed after biopsy with immunohistochemical stains. Treatment included selective intra-arterial embolization. RESULTS: A significant reduction in tumor burden was seen 3 months after intra-arterial embolization. No complications were associated with the treatment. CONCLUSION: Selective intra-arterial embolization may allow adequate palliative therapy in select cases of advanced extrascleral uveal melanoma.
PURPOSE: To report a treatment approach for advanced extrascleral uveal melanoma. METHODS: We performed clinical examination including magnetic resonance imaging, computed tomography, angiography, and histopathologic analysis. CASE: A 49-year-old healthy woman presented with a 7-year history of an enlarging pigmented mass in her right orbit. Malignant melanoma was diagnosed after biopsy with immunohistochemical stains. Treatment included selective intra-arterial embolization. RESULTS: A significant reduction in tumor burden was seen 3 months after intra-arterial embolization. No complications were associated with the treatment. CONCLUSION: Selective intra-arterial embolization may allow adequate palliative therapy in select cases of advanced extrascleral uveal melanoma.
Authors: Paul T Finger; Lawrence B Tena; Ekaterina Semenova; Paul Aridgides; Walter H Choi Journal: Brachytherapy Date: 2013-10-18 Impact factor: 2.362
Authors: Charles C Wykoff; Timothy G Murray; Arnold M Markoe; Lynn G Feun; Amy C Schefler; Steven Gayer Journal: Am J Ophthalmol Date: 2011-06 Impact factor: 5.258
Authors: Samira Khan; Paul T Finger; Guo-Pei Yu; Lubna Razzaq; Martine J Jager; Rob J W de Keizer; Per Sandkull; Stefan Seregard; Daniel Gologorsky; Amy C Schefler; Timothy G Murray; Tero Kivelä; Gian Paolo Giuliari; Hugh McGowan; E Rand Simpson; Christine Corriveau; Sarah E Coupland; Bertil E Damato Journal: Arch Ophthalmol Date: 2011-09-12