Literature DB >> 29344489

Caruncular Oncocytoma Mimicking Malignant Melanoma.

Thamolwan Surakiatchanukul1, Kareem Sioufi1, Renelle Pointdujour-Lim1, Ralph C Eagle2, Jerry A Shields1, Carol L Shields1.   

Abstract

PURPOSE: To report a case of pigmented caruncular oncocytoma that simulated malignant melanoma and discuss the associated ultrasonographic and pathologic features.
METHOD: Case report.
RESULTS: An 81-year-old female presented with a painless caruncular mass with a smooth brown surface suspicious for melanoma. Ultrasound biomicroscopy revealed a round mass with a large central cavity, more suggestive of a cystic rather than solid lesion. Following complete surgical resection, histopathology revealed a cystadenomatous lesion composed of bland cells with copious eosinophilic cytoplasm consistent with oncocytoma that had a central blood-filled cavity.
CONCLUSIONS: Oncocytoma is a benign tumor that can appear pigmented clinically and resemble melanoma. The definitive diagnosis requires histopathologic evaluation. Oncocytoma should be considered in the differential diagnosis of a pigmented caruncular mass.

Entities:  

Keywords:  Caruncle; Conjunctiva; Eye; Melanoma; Oncocytoma; Tumor; Ultrasound biomicroscopy

Year:  2017        PMID: 29344489      PMCID: PMC5757591          DOI: 10.1159/000468524

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  22 in total

1.  Lesions of the caruncle: a clinicohistopathologic study.

Authors:  C L Luthra; M T Doxanas; W R Green
Journal:  Surv Ophthalmol       Date:  1978 Nov-Dec       Impact factor: 6.048

Review 2.  Cavitary melanoma of ciliary body simulating a cyst.

Authors:  Junjun Zhang; Hakan Demirci; Carol L Shields; John A Leon; Jerry A Shields; Ralph C Eagle
Journal:  Arch Ophthalmol       Date:  2005-04

3.  Ultrasound biomicroscopy of cystic and solid caruncular oncocytoma.

Authors:  Yusuf Uysal; Carol L Shields; Arman Mashayekhi; Jerry A Shields; Ralph C Eagle
Journal:  Arch Ophthalmol       Date:  2006-11

4.  Cystic retinoblastoma.

Authors:  J Ginsberg; A G Spaulding; T Asbury
Journal:  Am J Ophthalmol       Date:  1975-11       Impact factor: 5.258

Review 5.  Lesions of the lacrimal caruncle with an emphasis on oncocytoma.

Authors:  Jyoti P Kapil; Alan D Proia; Puja Kumari Puri
Journal:  Am J Dermatopathol       Date:  2011-05       Impact factor: 1.533

6.  Oncocytomas (oxyphil adenomas) of the lacrimal caruncle.

Authors:  I G Rennie
Journal:  Br J Ophthalmol       Date:  1980-12       Impact factor: 4.638

7.  Oncocytic lesions of the ophthalmic region: a clinicopathological study with emphasis on cytokeratin expression.

Authors:  Jens Østergaard; Jan U Prause; Steffen Heegaard
Journal:  Acta Ophthalmol       Date:  2011-05       Impact factor: 3.761

Review 8.  Lesions of the caruncle: a description of 42 cases and a review of the literature.

Authors:  J Levy; M Ilsar; Y Deckel; A Maly; J Pe'er
Journal:  Eye (Lond)       Date:  2008-10-17       Impact factor: 3.775

Review 9.  Tumors of the conjunctiva and cornea.

Authors:  Carol L Shields; Jerry A Shields
Journal:  Surv Ophthalmol       Date:  2004 Jan-Feb       Impact factor: 6.048

10.  Oncocytoma of the caruncle.

Authors:  C L Shields; J A Shields; V Arbizo; J J Augsburger
Journal:  Am J Ophthalmol       Date:  1986-09-15       Impact factor: 5.258

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  3 in total

1.  Oncocytic lesions of the ocular adnexa: A review of the histopathology with a brief discussion of the pathogenesis.

Authors:  John G Heathcote; Curtis W Archibald; Alejandra A Valenzuela
Journal:  Saudi J Ophthalmol       Date:  2022-04-18

Review 2.  Rare Diseases of the Orbit.

Authors:  Ulrich Kisser; Jens Heichel; Alexander Glien
Journal:  Laryngorhinootologie       Date:  2021-04-30       Impact factor: 1.057

3.  Clinico-pathological correlation of lacrimal caruncle tumors: a retrospective analysis over 22 years at the University Eye Hospital Bonn.

Authors:  A C Clemens; K U Loeffler; F G Holz; M C Herwig-Carl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-10-28       Impact factor: 3.117

  3 in total

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