Literature DB >> 29344480

Primary Conjunctival Tuberculosis Presenting as Dry Eye: A Rare Case Report and Review of the Literature.

Rupinder Kaur Brar1, Ashok Singh1, Archana Hemant Deshpande1, Chitrawati Bal Gargade1, Sujit Das2.   

Abstract

Primary conjunctival tuberculosis is very rare in the developed countries. In an endemic country like India, it should be considered in the differential diagnosis of any unusual conjunctival lesion with unilaterality, chronicity, and nonresolution of symptoms after steroid use. We present the case of a 52-year-old female who presented with unilateral itching and blurring of vision for 20 days. There were irregular nodular elevated areas with shrinkage of the lower palpebral conjunctiva. A biopsy of the lesion revealed necrotizing epithelioid cell granulomas along with Langhans type of giant cells. However, no acid-fast bacilli were seen on Ziehl-Neelsen stain. Systemic examination of the patient was normal, and there was no evidence of pulmonary tuberculosis. Polymerase chain reaction of conjunctival scrapings was positive for Mycobacterium tuberculosis. The patient was started on antitubercular drugs. We present this very rare case of primary tuberculosis of the conjunctiva presenting with dryness of the eye.

Entities:  

Keywords:  Conjunctiva; Granulomas; Histopathology; Tuberculosis

Year:  2017        PMID: 29344480      PMCID: PMC5757551          DOI: 10.1159/000464467

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  4 in total

Review 1.  Primary tuberculosis of the conjunctiva.

Authors:  D Salas; S Murthy; C Champ; N Hawksworth
Journal:  Eye (Lond)       Date:  2001-10       Impact factor: 3.775

2.  Primary tuberculosis of the conjunctiva.

Authors:  A A GOLDFARB; I SELTZER
Journal:  Am J Dis Child       Date:  1946-08

Review 3.  Diagnosis of ocular tuberculosis: a role for new testing modalities?

Authors:  Carolyn T Bramante; Elizabeth A Talbot; Sivakumar R Rathinam; Rosalind Stevens; Michael E Zegans
Journal:  Int Ophthalmol Clin       Date:  2007

4.  Primary conjunctival tuberculosis in a 14 year old girl.

Authors:  Jeyanth Suresh Rose; Anupriya Arthur; Renu Raju; Meera Thomas
Journal:  Indian J Tuberc       Date:  2011-01
  4 in total
  1 in total

1.  Tuberculous corneal ulcer with hypopyon: A case report.

Authors:  Neethu Latiff; Meena Lakshmipathy; M K Janani; Parthopratim Dutta Majumder
Journal:  Indian J Ophthalmol       Date:  2020-05       Impact factor: 1.848

  1 in total

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