Christoffer Dellgren1, Mark H Yazer2, Ulrik Sprogøe1. 1. Department of Clinical Immunology, Odense University Hospital, Odense, Denmark. 2. The Institute for Transfusion Medicine, Department of Pathology, University of Pittsburgh, Pittsburg, PA, USA.
Abstract
BACKGROUND: Comparing the ABO and RhD group of a recipient's current pre-transfusion sample against their historical group is an important means of detecting wrong blood in tube (WBIT) errors. This study investigated the utility of using the donor ABO and RhD group as the historical check for recipients. METHODS: A single database stores serological information on blood donors, pregnant women, and patients throughout southern Denmark. A donor ABO and RhD group can be the historical blood group should that donor later require a transfusion. This database was searched to determine how often the ABO and RhD group on a recipient's current pre-transfusion sample was discrepant with their historical donor-derived blood group. RESULTS: During about 21 years, ABO and RhD groupings were performed on 76,455 blood donors and on 424,697 patients. There were 13,630/424,697 (3.2%) patients who had their donor-derived ABO and RhD group used as the historical comparison with the current sample; 6/13,630 (0.04%) of the current pre-transfusion samples on these patients were discrepant with the donor-derived historical group because of WBIT errors. Seven other discrepancies with the donor-derived blood group were also found. CONCLUSION: Accessing the donor-derived ABO and RhD group can be an important safeguard against WBIT-mediated mistransfusions.
BACKGROUND: Comparing the ABO and RhD group of a recipient's current pre-transfusion sample against their historical group is an important means of detecting wrong blood in tube (WBIT) errors. This study investigated the utility of using the donor ABO and RhD group as the historical check for recipients. METHODS: A single database stores serological information on blood donors, pregnant women, and patients throughout southern Denmark. A donor ABO and RhD group can be the historical blood group should that donor later require a transfusion. This database was searched to determine how often the ABO and RhD group on a recipient's current pre-transfusion sample was discrepant with their historical donor-derived blood group. RESULTS: During about 21 years, ABO and RhD groupings were performed on 76,455 blood donors and on 424,697 patients. There were 13,630/424,697 (3.2%) patients who had their donor-derived ABO and RhD group used as the historical comparison with the current sample; 6/13,630 (0.04%) of the current pre-transfusion samples on these patients were discrepant with the donor-derived historical group because of WBIT errors. Seven other discrepancies with the donor-derived blood group were also found. CONCLUSION: Accessing the donor-derived ABO and RhD group can be an important safeguard against WBIT-mediated mistransfusions.
Authors: Lawrence T Goodnough; Maurene Viele; Magali J Fontaine; Christine Jurado; Nancy Stone; Peter Quach; Lee Chua; Mei-Ling Chin; Robert Scott; Irina Tokareva; Kevin Tabb; Paul J Sharek Journal: Transfusion Date: 2009-03-31 Impact factor: 3.157
Authors: W H Dzik; M F Murphy; G Andreu; N Heddle; C Hogman; R Kekomaki; S Murphy; M Shimizu; C T Smit-Sibinga Journal: Vox Sang Date: 2003-07 Impact factor: 2.144