Literature DB >> 29343663

The Efficacy of VATS and Intrapleural Fibrinolytic Therapy in Parapneumonic Empyema Treatment.

Ozgur Samancilar1, Tevfik İlker Akçam2, Seyda Ors Kaya1, Ozgur Ozturk1, Onur Akcay3, Kenan Can Ceylan1.   

Abstract

BACKGROUND: Development of multiloculation-septation is a challenging entity in empyema patients. In this study, it is aimed to investigate the success rates of videothoracoscopic deloculation (VATS-D) and intrapleural fibrinolytic (IPFib) application after tube thoracostomy.
METHODS: The study retrospectively examined the patients diagnosed with empyema with multiloculation and septation between January 2005 and December 2014. Among these patients, the study included those who received VATS-D or IPFib therapy.
RESULTS: VATS-D (Group 1) was applied to 54 patients and IPFib (Group 2) was applied to 24 patients. The success of both procedures was evaluated considering the need of decortication in the following periods. In the VATS-D group, 4 (7.4%) patients required decortication via thoracotomy where it was 1 (4.1%) patient (p = 0.577) in the IPFib group. The length of hospital stay was 6.81 ± 2.55 (4-15) days in Group 1 compared to 14.25 ± 6.44 (7-27) days in Group 2 (p <0.001).
CONCLUSIONS: It was demonstrated that both of the methods applied in the study have high efficacy and are preferable methods based on the general conditions of patients. Additionally, the shorter length of hospital stays in patients received VATS-D was established as a significant parameter.

Entities:  

Keywords:  empyema; fibrinolytic therapy; operation; videothoracoscopy

Mesh:

Substances:

Year:  2018        PMID: 29343663      PMCID: PMC5833136          DOI: 10.5761/atcs.oa.17-00153

Source DB:  PubMed          Journal:  Ann Thorac Cardiovasc Surg        ISSN: 1341-1098            Impact factor:   1.520


  12 in total

1.  Efficacy of intrapleural tissue-type plasminogen activator in the treatment of loculated parapneumonic effusions.

Authors:  Darryl A Zuckerman; Michael F Reed; John A Howington; Jonathan S Moulton
Journal:  J Vasc Interv Radiol       Date:  2009-06-28       Impact factor: 3.464

2.  A randomized trial of empyema therapy.

Authors:  M A Wait; S Sharma; J Hohn; A Dal Nogare
Journal:  Chest       Date:  1997-06       Impact factor: 9.410

Review 3.  Efficacy of intrapleural instillation of fibrinolytics for treating pleural empyema and parapneumonic effusion: a meta-analysis of randomized control trials.

Authors:  Wencheng Nie; Yanru Liu; Jian Ye; Liuhong Shi; Fangchun Shao; Kejing Ying; Ruifeng Zhang
Journal:  Clin Respir J       Date:  2014-01-16       Impact factor: 2.570

Review 4.  A new classification of parapneumonic effusions and empyema.

Authors:  R W Light
Journal:  Chest       Date:  1995-08       Impact factor: 9.410

5.  Video-assisted thoracoscopic surgery in the treatment of complicated parapneumonic effusions or empyemas: outcome of 234 patients.

Authors:  Shi-Ping Luh; Ming-Chih Chou; Liang-Shun Wang; Jia-Yuh Chen; Tsong-Po Tsai
Journal:  Chest       Date:  2005-04       Impact factor: 9.410

6.  The role of video-assisted thoracoscopic surgery in the treatment of parapneumonic empyema after the failure of fibrinolytics.

Authors:  D Bouros; K M Antoniou; G Chalkiadakis; J Drositis; I Petrakis; N Siafakas
Journal:  Surg Endosc       Date:  2001-10-19       Impact factor: 4.584

7.  Recombinant tissue plasminogen activator in the treatment of pleural infections in adults.

Authors:  Marios E Froudarakis; George Kouliatsis; Paschalis Steiropoulos; Stavros Anevlavis; Athanasia Pataka; Maria Popidou; Demitrios Mikroulis; Ioannis Pneumatikos; Demosthenes Bouros
Journal:  Respir Med       Date:  2008-09-27       Impact factor: 3.415

Review 8.  Recommendations of diagnosis and treatment of pleural effusion. Update.

Authors:  Victoria Villena Garrido; Enrique Cases Viedma; Alberto Fernández Villar; Alicia de Pablo Gafas; Esteban Pérez Rodríguez; José Manuel Porcel Pérez; Francisco Rodríguez Panadero; Carlos Ruiz Martínez; Angel Salvatierra Velázquez; Luis Valdés Cuadrado
Journal:  Arch Bronconeumol       Date:  2014-03-31       Impact factor: 4.872

9.  Intrapleural use of tissue plasminogen activator and DNase in pleural infection.

Authors:  Najib M Rahman; Nicholas A Maskell; Alex West; Richard Teoh; Anthony Arnold; Carolyn Mackinlay; Daniel Peckham; Chris W H Davies; Nabeel Ali; William Kinnear; Andrew Bentley; Brennan C Kahan; John M Wrightson; Helen E Davies; Clare E Hooper; Y C Gary Lee; Emma L Hedley; Nicky Crosthwaite; Louise Choo; Emma J Helm; Fergus V Gleeson; Andrew J Nunn; Robert J O Davies
Journal:  N Engl J Med       Date:  2011-08-11       Impact factor: 91.245

10.  U.K. Controlled trial of intrapleural streptokinase for pleural infection.

Authors:  Nicholas A Maskell; Christopher W H Davies; Andrew J Nunn; Emma L Hedley; Fergus V Gleeson; Robert Miller; Rhian Gabe; Glyn L Rees; Timothy E A Peto; Mark A Woodhead; Donald J Lane; Janet H Darbyshire; Robert J O Davies
Journal:  N Engl J Med       Date:  2005-03-03       Impact factor: 91.245

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  5 in total

1.  Efficacy of video-assisted thoracoscopic surgery versus intrapleural streptokinase for treatment of parapneumonic empyema with multiloculation and septation.

Authors:  Reza Ershadi; Matin Vahedi; Shahab Rafieian
Journal:  Kardiochir Torakochirurgia Pol       Date:  2022-06-29

2.  Clinical Analysis of Video-Assisted Thoracoscopic Surgery for Resection of Solitary Pulmonary Nodules and Influencing Factors in the Diagnosis of Benign and Malignant Nodules.

Authors:  Hongxu Yue; Kaijie Fan; Zhimin Zhang; Yang Liu
Journal:  Evid Based Complement Alternat Med       Date:  2021-08-30       Impact factor: 2.629

3.  Can intrapleural alteplase treatment be an alternative to videothoracoscopic deloculation and decortication in pleural empyema?

Authors:  Tayfun Kermenli; Cebrail Azar
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2021-02-24       Impact factor: 1.195

Review 4.  From Bedside to the Bench-A Call for Novel Approaches to Prognostic Evaluation and Treatment of Empyema.

Authors:  Sophia Karandashova; Galina Florova; Steven Idell; Andrey A Komissarov
Journal:  Front Pharmacol       Date:  2022-01-20       Impact factor: 5.810

5.  VATS and Intrapleural Fibrinolytic Therapy for Parapneumonic Empyema.

Authors:  Gen Ohara; Kesato Iguchi; Hiroaki Satoh
Journal:  Ann Thorac Cardiovasc Surg       Date:  2018-07-02       Impact factor: 1.520

  5 in total

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