Literature DB >> 29339907

Trends, Challenges, and Opportunities Regarding Research in Non-traumatic Spinal Cord Dysfunction.

Peter Wayne New1,2,3, Sara J T Guilcher4,5, Susan B Jaglal5,6,7, Fin Biering-Sørensen8, Vanessa K Noonan9, Chester Ho10,11.   

Abstract

Background: Spinal cord dysfunction (SCDys) is caused by heterogeneous health conditions, and the incidence is increasing. Despite the growing interest in rehabilitation research for SCDys, research into SCDys faces many challenges. Objective: The objective of this project was to perform a clinical review of changes in SCDys research over the last 4 decades; identify challenges to conducting research in SCDys; and propose opportunities for improving research in SCDys.
Methods: A triangulation approach was used for obtaining evidence: literature search (January 2017) using MEDLINE and Embase databases for publications in English (1974-2016) regarding SCDys; workshop discussions at the International Spinal Cord Society annual meeting, September 16, 2016, Vienna, Austria; and our collective expertise in SCDys clinical rehabilitation research.
Results: There has been a substantial increase in publications on SCDys over the 4 decades, from 1,825 in 1974-1983 to 11,887 in the decade 2004-2013, along with an improvement in research methodology. Numerous challenges to research in SCDys rehabilitation were grouped into the following themes: (a) identification of cases; (b) study design and data collection; and (c) funding, preclinical, and international research. Opportunities for addressing these were identified. Conclusions: The increase in scientific publications on SCDys highlights the importance of this heterogeneous group among the research community. The overall lack of good quality epidemiological studies regarding incidence, prevalence, and survival in these patients serves as a benchmark for guiding improvements to inform evidence-based care and policy.

Entities:  

Keywords:  epidemiology; health services; rehabilitation; research; spinal cord diseases; spinal cord dysfunction; spinal cord injury

Mesh:

Year:  2017        PMID: 29339907      PMCID: PMC5667428          DOI: 10.1310/sci2304-313

Source DB:  PubMed          Journal:  Top Spinal Cord Inj Rehabil        ISSN: 1082-0744


  55 in total

1.  Epidemiology of spinal cord lesions in Denmark.

Authors:  E Biering-Sørensen; V Pedersen; S Clausen
Journal:  Paraplegia       Date:  1990-02

Review 2.  Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics.

Authors:  M H Tuszynski; J D Steeves; J W Fawcett; D Lammertse; M Kalichman; C Rask; A Curt; J F Ditunno; M G Fehlings; J D Guest; P H Ellaway; N Kleitman; P F Bartlett; A R Blight; V Dietz; B H Dobkin; R Grossman; A Privat
Journal:  Spinal Cord       Date:  2006-12-19       Impact factor: 2.772

3.  International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting.

Authors:  F Biering-Sørensen; M J DeVivo; S Charlifue; Y Chen; P W New; V Noonan; M W M Post; L Vogel
Journal:  Spinal Cord       Date:  2017-05-30       Impact factor: 2.772

4.  Swiss national community survey on functioning after spinal cord injury: Protocol, characteristics of participants and determinants of non-response.

Authors:  Martin W G Brinkhof; Christine Fekete; Jonviea D Chamberlain; Marcel W M Post; Armin Gemperli
Journal:  J Rehabil Med       Date:  2016-02       Impact factor: 2.912

5.  Photochemically induced spinal cord injury in the rat.

Authors:  B D Watson; R Prado; W D Dietrich; M D Ginsberg; B A Green
Journal:  Brain Res       Date:  1986-03-05       Impact factor: 3.252

Review 6.  Application of the Andersen's health care utilization framework to secondary complications of spinal cord injury: a scoping review.

Authors:  Sara J T Guilcher; B Cathy Craven; Mary Ann McColl; Louise Lemieux-Charles; Tiziana Casciaro; Susan B Jaglal
Journal:  Disabil Rehabil       Date:  2011-11-16       Impact factor: 3.033

Review 7.  Setting the stage for functional repair of spinal cord injuries: a cast of thousands.

Authors:  L M Ramer; M S Ramer; J D Steeves
Journal:  Spinal Cord       Date:  2005-03       Impact factor: 2.772

Review 8.  Using administrative data to study persons with disabilities.

Authors:  Lisa I Iezzoni
Journal:  Milbank Q       Date:  2002       Impact factor: 4.911

9.  Characteristics, length of stay and functional outcome of patients with spinal cord injury in Dutch and Flemish rehabilitation centres.

Authors:  R Osterthun; M W M Post; F W A van Asbeck
Journal:  Spinal Cord       Date:  2008-11-11       Impact factor: 2.772

Review 10.  Standardization of Data for Clinical Use and Research in Spinal Cord Injury.

Authors:  Fin Biering-Sørensen; Vanessa K Noonan
Journal:  Brain Sci       Date:  2016-08-12
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  4 in total

1.  Survival after non-traumatic spinal cord injury: evidence from a population-based rehabilitation cohort in Switzerland.

Authors:  A Buzzell; J D Chamberlain; H P Gmünder; K Hug; X Jordan; M Schubert; M W G Brinkhof
Journal:  Spinal Cord       Date:  2018-11-09       Impact factor: 2.772

Review 2.  A Narrative Review of Pediatric Nontraumatic Spinal Cord Dysfunction.

Authors:  Peter Wayne New
Journal:  Top Spinal Cord Inj Rehabil       Date:  2019

Review 3.  Describing the current state of post-rehabilitation health system surveillance in Ontario - an invited review.

Authors:  Chip P Rowan; Brian C F Chan; Susan B Jaglal; B Catharine Craven
Journal:  J Spinal Cord Med       Date:  2019-10       Impact factor: 1.985

4.  All-cause and cause-specific mortality following non-traumatic spinal cord injury: evidence from a population-based cohort study in Switzerland.

Authors:  A Buzzell; J D Chamberlain; I Eriks-Hoogland; K Hug; X Jordan; M Schubert; M Zwahlen; M W G Brinkhof
Journal:  Spinal Cord       Date:  2019-10-07       Impact factor: 2.772

  4 in total

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