Literature DB >> 29338221

Synthetic Strategy toward the Pentacyclic Core of Melodinus Alkaloids.

Navya Goli1, Shivakrishna Kallepu, Prathama S Mainkar1, Jerripothula K Lakshmi, Rambabu Chegondi1, Srivari Chandrasekhar1.   

Abstract

The three-component Povarov reaction is efficiently utilized for construction of the pentacyclic framework of complex Melodinus alkaloids, which is amenable to expansion to other complex natural products. The key steps were Povarov reaction, one-pot reductive cyclization, and ring-closing metathesis (RCM) reaction.

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Year:  2018        PMID: 29338221     DOI: 10.1021/acs.joc.7b03138

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Sc(OTf)3-Mediated [4 + 2] Annulations of N-Carbonyl Aryldiazenes with Cyclopentadiene to Construct Cinnoline Derivatives: Azo-Povarov Reaction.

Authors:  Xabier Jiménez-Aberásturi; Francisco Palacios; Jesús M de Los Santos
Journal:  J Org Chem       Date:  2022-08-16       Impact factor: 4.198

  1 in total

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