Mahima Akula1, Alexandra Kulikova1, David A Khan2, E Sherwood Brown1. 1. a Department of Psychiatry , The University of Texas Southwestern Medical Center , Dallas , TX , USA. 2. b Department of Internal Medicine , The University of Texas Southwestern Medical Center , Dallas , TX , USA.
Abstract
OBJECTIVE: Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. METHODS: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. RESULTS: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280-2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106-2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. CONCLUSIONS: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthma patients and suggest further research in this area is needed.
OBJECTIVE:Asthma is an increasingly prevalent disease that is associated with substantial physical and financial burdens. Additionally, asthma is linked to psychiatric disorders. This study examines the relationship between asthma diagnosis, current depressive symptoms, and lifetime psychiatric disorder history in a large, community-based sample. METHODS: We analyzed data from 2168 participants in the Dallas Heart Study, a large, diverse, community-based sample of people designed to be representative of the Dallas County population. Logistic regressions analyzing the relationship between asthma diagnosis and history of a psychiatric disorder, as well as between asthma diagnosis and the Quick Inventory of Depressive Symptomatology (QIDS) scores were performed, controlling for demographic data. RESULTS: 13.4% of the sample had an asthma diagnosis. Asthma diagnosis was significantly associated with a history of nervous, emotional, or mental health disorder diagnosis [OR 1.810 (95% CI 1.280-2.559) p = 0.001], and with QIDS scores consistent with moderate or greater current depressive symptom severity [OR 1.586 (95%CI 1.106-2.274) p = 0.012]. The relationships were not moderated by age, gender, race, smoking status, or Body Mass Index. CONCLUSIONS: A diagnosis of asthma may be associated with current clinically significant levels of depressive symptoms and a lifetime psychiatric disorder. The current report adds to the existing literature in this area by assessing both current and lifetime symptoms and by using a large and diverse population. The findings highlight the clinical importance of considering the possibility of psychiatric illness in asthmapatients and suggest further research in this area is needed.
Entities:
Keywords:
Management/control; morbidity and mortality; quality of life
Authors: M Z Wamboldt; J K Hewitt; S Schmitz; F S Wamboldt; M Räsänen; M Koskenvuo; K Romanov; J Varjonen; J Kaprio Journal: Am J Med Genet Date: 2000-04-03
Authors: R D Goodwin; M Robinson; P D Sly; I W McKeague; E S Susser; S R Zubrick; F J Stanley; E Mattes Journal: Psychol Med Date: 2012-08-29 Impact factor: 7.723
Authors: Marleen M H J van Gelder; Naomi P E Schouten; Peter J F M Merkus; Chris M Verhaak; Nel Roeleveld; Jolt Roukema Journal: J Med Internet Res Date: 2015-06-16 Impact factor: 5.428
Authors: Jeffrey L Voorhees; Andrew J Tarr; Eric S Wohleb; Jonathan P Godbout; Xiaokui Mo; John F Sheridan; Timothy D Eubank; Clay B Marsh Journal: PLoS One Date: 2013-03-08 Impact factor: 3.240
Authors: Zhenxing Xu; Fei Wang; Prakash Adekkanattu; Budhaditya Bose; Veer Vekaria; Pascal Brandt; Guoqian Jiang; Richard C Kiefer; Yuan Luo; Jennifer A Pacheco; Luke V Rasmussen; Jie Xu; George Alexopoulos; Jyotishman Pathak Journal: Learn Health Syst Date: 2020-08-03
Authors: Jonathan M Feldman; Jacqueline Becker; Arushi Arora; Jesenya DeLeon; Tatiana Torres-Hernandez; Naomi Greenfield; Allyana Wiviott; Sunit Jariwala; Chang Shim; Alex D Federman; Juan P Wisnivesky Journal: Psychosom Med Date: 2021-09-01 Impact factor: 3.864