Literature DB >> 29336591

Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia.

Wasana Prasitsuebsai1, Chuenkamol Sethaputra2, Pagakrong Lumbiganon3, Rawiwan Hansudewechakul4, Kulkanya Chokephaibulkit5, Khanh Huu Truong6, Lam Van Nguyen7, Kamarul Azahar Mohd Razali8, Nik Khairulddin Nik Yusoff9, Moy Siew Fong10, Sirinya Teeraananchai1, Jintanat Ananworanich11,12,13,14, Nicolas Durier2,15.   

Abstract

We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA >1000 copies/mL; 19% reported adherence <80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p = 0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA >1000 copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

Entities:  

Keywords:  Asia; HIV; adherence; adolescents; stigma

Mesh:

Substances:

Year:  2018        PMID: 29336591      PMCID: PMC5912939          DOI: 10.1080/09540121.2018.1425363

Source DB:  PubMed          Journal:  AIDS Care        ISSN: 0954-0121


  31 in total

Review 1.  The Association of HIV-Related Stigma to HIV Medication Adherence: A Systematic Review and Synthesis of the Literature.

Authors:  Shannon M Sweeney; Peter A Vanable
Journal:  AIDS Behav       Date:  2016-01

Review 2.  Impact of HIV-Status Disclosure on Adherence to Antiretroviral Therapy Among HIV-Infected Children in Resource-Limited Settings: A Systematic Review.

Authors:  Justin Nichols; Alexis Steinmetz; Elijah Paintsil
Journal:  AIDS Behav       Date:  2017-01

3.  Long-term adherence to first-line highly active antiretroviral therapy in a hospital-based cohort: predictors and impact on virologic response and relapse.

Authors:  G Parruti; L Manzoli; P Marani Toro; G D'Amico; S Rotolo; V Graziani; F Schioppa; A Consorte; L Alterio; G Marani Toro; B A Boyle
Journal:  AIDS Patient Care STDS       Date:  2006-01       Impact factor: 5.078

4.  Disclosure of HIV/AIDS diagnosis to HIV-infected children in Thailand.

Authors:  Peninnah Oberdorfer; Thanyawee Puthanakit; Orawan Louthrenoo; Chawanun Charnsil; Virat Sirisanthana; Thira Sirisanthana
Journal:  J Paediatr Child Health       Date:  2006-05       Impact factor: 1.954

5.  A multisite randomized trial of a motivational intervention targeting multiple risks in youth living with HIV: initial effects on motivation, self-efficacy, and depression.

Authors:  Sylvie Naar-King; Jeffrey T Parsons; Debra Murphy; Karen Kolmodin; D Robert Harris
Journal:  J Adolesc Health       Date:  2010-02-04       Impact factor: 5.012

6.  Multiple risk behaviors among youth living with human immunodeficiency virus in five U.S. cities.

Authors:  Mary R Tanney; Sylvie Naar-King; Debra A Murphy; Jeffrey T Parsons; Heather Janisse
Journal:  J Adolesc Health       Date:  2009-08-18       Impact factor: 5.012

7.  Better adherence with once-daily antiretroviral regimens: a meta-analysis.

Authors:  Jean-Jacques Parienti; David R Bangsberg; Renaud Verdon; Edward M Gardner
Journal:  Clin Infect Dis       Date:  2009-02-15       Impact factor: 9.079

8.  Benefits of Disclosure of HIV Status to Infected Children and Adolescents: Perceptions of Caregivers and Health Care Providers.

Authors:  Eric Gyamfi; Paul Okyere; Emmanuel Appiah-Brempong; Rose Odotei Adjei; Kofi Akohene Mensah
Journal:  J Assoc Nurses AIDS Care       Date:  2015-08-10       Impact factor: 1.354

9.  Risk perceptions of STIs/HIV and sexual risk behaviours among sexually experienced adolescents in the northern part of Lao PDR.

Authors:  Vanphanom Sychareun; Sarah Thomsen; Kongmany Chaleunvong; Elisabeth Faxelid
Journal:  BMC Public Health       Date:  2013-12-05       Impact factor: 3.295

10.  Phased implementation of spaced clinic visits for stable HIV-positive patients in Rwanda to support Treat All.

Authors:  Sabin Nsanzimana; Eric Remera; Muhayimpundu Ribakare; Tracy Burns; Sibongile Dludlu; Edward J Mills; Jeanine Condo; Heiner C Bucher; Nathan Ford
Journal:  J Int AIDS Soc       Date:  2017-07-21       Impact factor: 5.396

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  7 in total

1.  Determinants of Viral Resuppression or Persistent Virologic Failure After Initial Failure With Second-Line Antiretroviral Treatment Among Asian Children and Adolescents With HIV.

Authors:  Sirinya Teeraananchai; Stephen J Kerr; Monica Gandhi; Viet Chau Do; Lam Van Nguyen; Dan Ngoc Hanh Tran; Pope Kosalaraksa; Thida Singtoroj; Narukjaporn Thammajaruk; Thidarat Jupimai; Annette H Sohn
Journal:  J Pediatric Infect Dis Soc       Date:  2020-04-30       Impact factor: 3.164

2.  A Longitudinal Study of Behavioral Risk, Adherence, and Virologic Control in Adolescents Living With HIV in Asia.

Authors:  Jeremy L Ross; Sirinya Teeraananchai; Pagakrong Lumbiganon; Rawiwan Hansudewechakul; Kulkanya Chokephaibulkit; Truong Huu Khanh; Lam Van Nguyen; Thahira A Jamal Mohamed; Nik Khairulddin Nik Yusoff; Moy Siew Fong; Wasana Prasitsuebsai; Annette H Sohn; Stephen J Kerr
Journal:  J Acquir Immune Defic Syndr       Date:  2019-06-01       Impact factor: 3.731

3.  The Impact of Formal and Informal Institutions on ART Drug Adherence.

Authors:  Diribe Makonene Kumsa; Gudina Terefe Tucho
Journal:  J Int Assoc Provid AIDS Care       Date:  2019 Jan-Dec

4.  Monitoring adherence to antiretroviral therapy among adolescents in Southern Uganda: comparing Wisepill to Self-report in predicting viral suppression in a cluster-randomized trial.

Authors:  Samuel Kizito; Flavia Namuwonge; Rachel Brathwaite; Torsten B Neilands; Proscovia Nabunya; Ozge Sensoy Bahar; Christopher Damulira; Abel Mwebembezi; Claude Mellins; Mary M McKay; Fred M Ssewamala
Journal:  J Int AIDS Soc       Date:  2022-09       Impact factor: 6.707

Review 5.  Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis.

Authors:  Phoebe Pui Ying Lam; Ni Zhou; Cynthia Kar Yung Yiu; Hai Ming Wong
Journal:  Int J Environ Res Public Health       Date:  2022-09-21       Impact factor: 4.614

6.  Neurobehavioral outcomes in young adults with perinatally acquired HIV.

Authors:  Paulina Coutifaris; Desiree Byrd; Jocelyn Childs; Uraina Clark; Roberto Posada; Reuben Robbins; Susan Morgello
Journal:  AIDS       Date:  2020-11-15       Impact factor: 4.632

7.  Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop.

Authors:  Dana Gabuzda; Beth D Jamieson; Ronald G Collman; Michael M Lederman; Tricia H Burdo; Steven G Deeks; Dirk P Dittmer; Howard S Fox; Nicholas T Funderburg; Savita G Pahwa; Ivona Pandrea; Cara C Wilson; Peter W Hunt
Journal:  Pathog Immun       Date:  2020-06-17
  7 in total

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