H Zhao1, Gang Liu, S Wei, H Liu. 1. Jilin Cancer Hospital, Changchun, Jilin 130012, People's Republic of China.
Abstract
PURPOSE: In recent years, there has been an increase in the number of elderly patients undergoing surgery for esophageal squamous cell carcinoma (ESCC). However, there are few studies on short- and long-term outcomes of minimally invasive esophagectomy (MIE) in such patients. The purpose of this study was to report both short- and long-term outcomes of MIE in elderly patients with ESCC. METHODS: A total of 273 patients with ESCC underwent MIE at our hospital from January 2010 to December 2016. Patients were divided into elderly (≥70 years) and nonelderly (<70 years) groups based on age at the time of surgery. Groups were compared with regard to general preoperative data, intraoperative data, postoperative 30-day complications and their severity, pathological result, recurrence, overall survival (OS), and disease-free survival (DFS) rates. RESULTS: The elderly group was characterized by higher Charlson Comorbidity Index >2 and American Society of Anesthesiologists (ASA) grade. Comparisons of other general preoperative data showed no significant differences. In addition, there were no significant differences in short-term outcomes except for postoperative 30-day complication rate. Although 30-day postoperative complication rate was higher in the elderly group compared with the nonelderly group, the incidence of major complications was similar between groups. Cancer recurrence, 5-year OS, and 5-year DFS rates also were similar between groups. CONCLUSION: Although elderly patients with ESCC had higher Charlson Comorbidity Index and ASA grade, they could achieve short- and long-term outcomes of MIE similar to those of nonelderly patients.
PURPOSE: In recent years, there has been an increase in the number of elderly patients undergoing surgery for esophageal squamous cell carcinoma (ESCC). However, there are few studies on short- and long-term outcomes of minimally invasive esophagectomy (MIE) in such patients. The purpose of this study was to report both short- and long-term outcomes of MIE in elderly patients with ESCC. METHODS: A total of 273 patients with ESCC underwent MIE at our hospital from January 2010 to December 2016. Patients were divided into elderly (≥70 years) and nonelderly (<70 years) groups based on age at the time of surgery. Groups were compared with regard to general preoperative data, intraoperative data, postoperative 30-day complications and their severity, pathological result, recurrence, overall survival (OS), and disease-free survival (DFS) rates. RESULTS: The elderly group was characterized by higher Charlson Comorbidity Index >2 and American Society of Anesthesiologists (ASA) grade. Comparisons of other general preoperative data showed no significant differences. In addition, there were no significant differences in short-term outcomes except for postoperative 30-day complication rate. Although 30-day postoperative complication rate was higher in the elderly group compared with the nonelderly group, the incidence of major complications was similar between groups. Cancer recurrence, 5-year OS, and 5-year DFS rates also were similar between groups. CONCLUSION: Although elderly patients with ESCC had higher Charlson Comorbidity Index and ASA grade, they could achieve short- and long-term outcomes of MIE similar to those of nonelderly patients.
Authors: Nikolaj S Baranov; Cettela Slootmans; Frans van Workum; Bastiaan R Klarenbeek; Yvonne Schoon; Camiel Rosman Journal: World J Gastrointest Oncol Date: 2021-02-15
Authors: Robert T van Kooten; Daan M Voeten; Ewout W Steyerberg; Henk H Hartgrink; Mark I van Berge Henegouwen; Richard van Hillegersberg; Rob A E M Tollenaar; Michel W J M Wouters Journal: Ann Surg Oncol Date: 2021-09-05 Impact factor: 5.344