| Literature DB >> 29329958 |
Chris Rorres1, Maria Romano2, Jennifer A Miller3, Jana M Mossey4, Tony H Grubesic5, David E Zellner6, Gary Smith7.
Abstract
Contact tracing is a crucial component of the control of many infectious diseases, but is an arduous and time consuming process. Procedures that increase the efficiency of contact tracing increase the chance that effective controls can be implemented sooner and thus reduce the magnitude of the epidemic. We illustrate a procedure using Graph Theory in the context of infectious disease epidemics of farmed animals in which the epidemics are driven mainly by the shipment of animals between farms. Specifically, we created a directed graph of the recorded shipments of deer between deer farms in Pennsylvania over a timeframe and asked how the properties of the graph could be exploited to make contact tracing more efficient should Chronic Wasting Disease (a prion disease of deer) be discovered in one of the farms. We show that the presence of a large strongly connected component in the graph has a significant impact on the number of contacts that can arise.Entities:
Keywords: Chronic Wasting Disease; Contact tracing; Directed graphs; Strongly connected components
Mesh:
Year: 2017 PMID: 29329958 DOI: 10.1016/j.epidem.2017.12.006
Source DB: PubMed Journal: Epidemics ISSN: 1878-0067 Impact factor: 4.396