Zhi Chen1, Jiaqi Zhou1, Xiaomei Qu1, Xingtao Zhou1, Feng Xue2. 1. Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health, China. 2. Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health, China. Electronic address: Lilyxue80@vip.163.com.
Abstract
PURPOSE: To investigate the effect of orthokeratology (ortho-k) lens wear on axial length (AL) growth in juvenile myopic anisometropes. METHODS: This retrospective study consisted of two parts. In Part One, 25 anisometropic participants (mean age, 11.2 ± 1.9 years; 11 females and 14 males) were fitted with ortho-k lenses in the more myopic eye only, and the rate of AL growth was compared between the ortho-k lens wearing eye and the untreated contralateral eye over an average period of 23.1 ± 8.3 months. In Part Two, 8 participants who developed myopia in the contralateral eye received ortho-k treatment in both eyes for an average of 12 months; the rate of AL growth before and after ortho-k treatment in the newly developed myopic eye was compared. RESULTS: In Part One, the rate of AL elongation in the ortho-k treated eye (0.08 ± 0.15 mm/year) was significantly slower than in the contralateral eye (0.39 ± 0.32 mm/year) (P < 0.001). At the completion of Part One, 16 out of 25 participants (64%) developed myopia in the initially non-myopic eye. In Part Two, the rate of AL elongation after ortho-k treatment in the newly developed myopic eye (0.20 mm/year) was significantly slower than that before ortho-k treatment in the same eye (0.49 mm/year) (P = 0.012). CONCLUSION: Ortho-k treatment slows AL growth in the more myopic eye of anisometropic patients; should the contralateral eye develop myopia in the future, ortho-k is capable of slowing down AL growth in that eye as well.
PURPOSE: To investigate the effect of orthokeratology (ortho-k) lens wear on axial length (AL) growth in juvenile myopic anisometropes. METHODS: This retrospective study consisted of two parts. In Part One, 25 anisometropic participants (mean age, 11.2 ± 1.9 years; 11 females and 14 males) were fitted with ortho-k lenses in the more myopic eye only, and the rate of AL growth was compared between the ortho-k lens wearing eye and the untreated contralateral eye over an average period of 23.1 ± 8.3 months. In Part Two, 8 participants who developed myopia in the contralateral eye received ortho-k treatment in both eyes for an average of 12 months; the rate of AL growth before and after ortho-k treatment in the newly developed myopic eye was compared. RESULTS: In Part One, the rate of AL elongation in the ortho-k treated eye (0.08 ± 0.15 mm/year) was significantly slower than in the contralateral eye (0.39 ± 0.32 mm/year) (P < 0.001). At the completion of Part One, 16 out of 25 participants (64%) developed myopia in the initially non-myopic eye. In Part Two, the rate of AL elongation after ortho-k treatment in the newly developed myopic eye (0.20 mm/year) was significantly slower than that before ortho-k treatment in the same eye (0.49 mm/year) (P = 0.012). CONCLUSION: Ortho-k treatment slows AL growth in the more myopic eye of anisometropic patients; should the contralateral eye develop myopia in the future, ortho-k is capable of slowing down AL growth in that eye as well.