Literature DB >> 29328907

Weaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes.

Bernard Mulvey1, Joseph D Dougherty2.   

Abstract

Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29328907     DOI: 10.1016/j.cell.2017.12.037

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  3 in total

1.  Cortical Neuron Migration and Dendrite Morphology are Regulated by Carboxypeptidase E.

Authors:  Chen Liang; Damien Carrel; Anton Omelchenko; Hyuck Kim; Aashini Patel; Isabelle Fanget; Bonnie L Firestein
Journal:  Cereb Cortex       Date:  2019-07-05       Impact factor: 5.357

2.  KIF5C deficiency causes abnormal cortical neuronal migration, dendritic branching, and spine morphology in mice.

Authors:  Wanxing Li; Tianling Cheng; Xinran Dong; Huiyao Chen; Lin Yang; Zilong Qiu; Wenhao Zhou
Journal:  Pediatr Res       Date:  2021-12-29       Impact factor: 3.953

3.  Cortactin deacetylation by HDAC6 and SIRT2 regulates neuronal migration and dendrite morphogenesis during cerebral cortex development.

Authors:  Ji-Ye Kim; Hee-Gon Hwang; Joo-Yong Lee; Minkyu Kim; Jeong-Yoon Kim
Journal:  Mol Brain       Date:  2020-07-25       Impact factor: 4.041

  3 in total

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