| Literature DB >> 29326001 |
Decio L Eizirik1, Anne Op de Beeck2.
Abstract
Enteroviruses are important environmental contributors to islet inflammation (insulitis) in type 1 diabetes mellitus (T1DM). A recent study characterized the proteomic alterations induced by Coxsackievirus type B (CVB) infection of human islets. This provides relevant information to decipher the words of the virus-induced 'dialog' between β cells and the immune system that leads to autoimmunity.Entities:
Keywords: coxsackievirus; diabetes mellitus; insulitis; pancreatic beta cells; pancreatic islets
Mesh:
Year: 2018 PMID: 29326001 DOI: 10.1016/j.tem.2017.12.002
Source DB: PubMed Journal: Trends Endocrinol Metab ISSN: 1043-2760 Impact factor: 12.015