BACKGROUND: To assess the total, gender-related and ageing process-related incidence rates of amyotrophic lateral sclerosis (ALS) in Beijing, China. Determine whether the decreased male to female ratio among postmenopausal age groups. METHODS: We used the 2-source capture-recapture method to estimate the incidence of ALS in Beijing. The primary and secondary data sources were from diagnostic hospitals and assisted care institutions in the same area from 2010 to 2015. RESULTS: A total of 562 cases and 283 cases were extracted from 2 data sources, and a total of 962 patients diagnosed with ALS within the 6-year period were estimated (95% CI 883-1041). The average yearly incidence was 0.77/100,000 persons (95% CI 0.71-0.83). The female to male ratio was 1.63. The incidence was associated with age and peaked in the 55-64 year age group. There was no obvious decline in the male:female ratio among postmenopausal age groups. CONCLUSIONS: The total incidence of ALS in Beijing is similar to international reports. The onset of ALS is not merely the result of ageing.
BACKGROUND: To assess the total, gender-related and ageing process-related incidence rates of amyotrophic lateral sclerosis (ALS) in Beijing, China. Determine whether the decreased male to female ratio among postmenopausal age groups. METHODS: We used the 2-source capture-recapture method to estimate the incidence of ALS in Beijing. The primary and secondary data sources were from diagnostic hospitals and assisted care institutions in the same area from 2010 to 2015. RESULTS: A total of 562 cases and 283 cases were extracted from 2 data sources, and a total of 962 patients diagnosed with ALS within the 6-year period were estimated (95% CI 883-1041). The average yearly incidence was 0.77/100,000 persons (95% CI 0.71-0.83). The female to male ratio was 1.63. The incidence was associated with age and peaked in the 55-64 year age group. There was no obvious decline in the male:female ratio among postmenopausal age groups. CONCLUSIONS: The total incidence of ALS in Beijing is similar to international reports. The onset of ALS is not merely the result of ageing.
Authors: Johannes Dorst; Lu Chen; Angela Rosenbohm; Dong-Sheng Fan; Albert C Ludolph; Jens Dreyhaupt; Annemarie Hübers; Joachim Schuster; Jochen H Weishaupt; Jan Kassubek; Burkhard Gess; Thomas Meyer; Ute Weyen; Andreas Hermann; Jürgen Winkler; Torsten Grehl; Tim Hagenacker; Paul Lingor; Jan C Koch; Anne Sperfeld; Susanne Petri; Julian Großkreutz; Moritz Metelmann; Joachim Wolf; Andrea S Winkler; Thomas Klopstock; Matthias Boentert; Siw Johannesen; Alexander Storch; Bertold Schrank; Daniel Zeller; Xiao-Lu Liu; Lu Tang Journal: J Neurol Date: 2019-03-28 Impact factor: 4.849
Authors: Adriaan D de Jongh; Ruben P A van Eijk; Susan M Peters; Michael A van Es; Anja M C Horemans; Anneke J van der Kooi; Nicol C Voermans; Roel C H Vermeulen; Jan H Veldink; Leonard H van den Berg Journal: Neurology Date: 2021-01-20 Impact factor: 9.910