Literature DB >> 29323634

Epidemiology of traumatic spinal cord injury in Tianjin, China: An 18-year retrospective study of 735 cases.

Hai-Liang Li1, Hong Xu1, Yu-Lin Li1, Shi-Wei Sun1, Wen-Ye Song1, Qiang Wu1, Jie Ai1, Jing-Cheng Sun1, Guang-Zhi Ning1, Shi-Qing Feng1.   

Abstract

Study Design: Hospital-based retrospective study
Objectives: To evaluate the pathogenetic features of traumatic spinal cord injury (TSCI) during 1999-2016 according to changed injury etiology with time, explore different characteristics of patients suffered a TSCI during 1999-2007 and 2008-2016 in Tianjin, China.Setting: Tianjin Medical University General Hospital
Methods: In this study, the medical records of TSCI patients were obtained from Tianjin Medical University General Hospital (TMUGH) from 1st January 1999 to 31th December 2016. Variables were recorded, including age, gender occupation, etiology, the level of injury, America Spinal Injury Association (ASIA) impairment scale, the severity, concomitant injuries, death and its cause. To explore the differences in characteristics by etiology and by two periods, related statistical methods were used to calculate the correlation of some variables. Differences in etiology of TSCI during 1999-2016 were evaluated and differences in epidemiological characteristics were separately compared and analyzed between the 1999-2007 period and the 2008-2016 period.
Results: From 1999-2016, 831 TSCI cases were identified and 96 cases were excluded from analyses. The male-to-female ratio was 2.9:1 and the mean age was 49.7±15.2 years, which changed significantly between 1999-2007 (45.1±14.2) and 2008-2016 (51.6±15.2). Traffic accidents (45.8%) were the leading cause of TSCI during the 1999-2007 period, followed by low falls (30.7%). However, the opposite result was observed during the 2008-2016 period. Significant difference was observed compared with thoracic, lumbar and sacral levels, cervical level was the most commonly affected levels and the percentage decreased to a certain degree between 1999-2007 and 2008-2016 (from 84.4% to 68.9%). The proportions of ASIA grades A, B, C, and D were 20.5%, 10.3%, 23.3%, and 45.9%, respectively. The percentage of complete tetraplegia decreased from 22.9% in 1999-2007 to 13.2% in 2008-2016, and the percentage of incomplete paraplegia increased from 9.7% to 27.9%.
Conclusion: According to the changes in the epidemiological characteristics of TSCI, relevant health service, laws and regulations, preventative strategies should be readjusted to follow up the changing situation and epidemiological characteristics of TSCI.

Entities:  

Keywords:  Changes; Epidemiological characteristics; Statistically significant difference; Traumatic spinal cord injury

Mesh:

Year:  2018        PMID: 29323634      PMCID: PMC6830263          DOI: 10.1080/10790268.2017.1415418

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  25 in total

1.  Epidemiology of traumatic spinal cord injury in Tianjin, China.

Authors:  G-Z Ning; T-Q Yu; S-Q Feng; X-H Zhou; D-X Ban; Y Liu; X-X Jiao
Journal:  Spinal Cord       Date:  2010-10-05       Impact factor: 2.772

2.  Incidence of traumatic spinal cord injury in Denmark, 1990-2012: a hospital-based study.

Authors:  B Bjørnshave Noe; E M Mikkelsen; R M Hansen; M Thygesen; E M Hagen
Journal:  Spinal Cord       Date:  2014-11-04       Impact factor: 2.772

3.  The economic burden of traumatic spinal cord injury in Canada.

Authors:  H Krueger; V K Noonan; L M Trenaman; P Joshi; C S Rivers
Journal:  Chronic Dis Inj Can       Date:  2013-06

4.  Epidemiology of traumatic spinal cord injuries in Austria 2002-2012.

Authors:  Marek Majdan; Alexandra Brazinova; Walter Mauritz
Journal:  Eur Spine J       Date:  2015-05-09       Impact factor: 3.134

Review 5.  Cell transplantation therapy for spinal cord injury.

Authors:  Peggy Assinck; Greg J Duncan; Brett J Hilton; Jason R Plemel; Wolfram Tetzlaff
Journal:  Nat Neurosci       Date:  2017-04-25       Impact factor: 24.884

6.  [Epidemiology of Spinal Cord Injury in Iceland from 1975 to 2014].

Authors:  Eyrún Arna Kristinsdottir; Sigrun Knutsdottir; Kristinn Sigvaldason; Halldor Jonsson; Pall E Ingvarsson
Journal:  Laeknabladid       Date:  2016-11       Impact factor: 0.548

7.  Traumatic spinal cord injury in the United States, 1993-2012.

Authors:  Nitin B Jain; Gregory D Ayers; Emily N Peterson; Mitchel B Harris; Leslie Morse; Kevin C O'Connor; Eric Garshick
Journal:  JAMA       Date:  2015-06-09       Impact factor: 56.272

8.  Epidemiological profile of 239 traumatic spinal cord injury cases over a period of 12 years in Tianjin, China.

Authors:  Hong-Yong Feng; Guang-Zhi Ning; Shi-Qing Feng; Tie-Qiang Yu; Heng-Xing Zhou
Journal:  J Spinal Cord Med       Date:  2011       Impact factor: 1.985

9.  Traumatic spinal cord injury in Tianjin, China: a single-center report of 354 cases.

Authors:  Y Zhou; X-B Wang; S-L Kan; G-Z Ning; Y-L Li; B Yang; Y Li; J-C Sun; S-Q Feng
Journal:  Spinal Cord       Date:  2015-10-13       Impact factor: 2.772

10.  Changing demographics of spinal cord injury over a 20-year period: a longitudinal population-based study in Scotland.

Authors:  E J McCaughey; M Purcell; A N McLean; M H Fraser; A Bewick; R J Borotkanics; D B Allan
Journal:  Spinal Cord       Date:  2015-10-13       Impact factor: 2.772

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1.  Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.

Authors:  Chenxi Zhao; Tiangang Zhou; Xiaoqing Zhao; Yilin Pang; Wenxiang Li; Baoyou Fan; Ming Li; Xinjie Liu; Lei Ma; Jiawei Zhang; Chao Sun; Wenyuan Shen; Xiaohong Kong; Xue Yao; Shiqing Feng
Journal:  J Neuroinflammation       Date:  2022-07-16       Impact factor: 9.587

2.  MicroRNA-139-5p Promotes Functional Recovery and Reduces Pain Hypersensitivity in Mice with Spinal Cord Injury by Targeting Mammalian Sterile 20-like Kinase 1.

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Journal:  Neurochem Res       Date:  2020-11-19       Impact factor: 3.996

3.  [Experimental study of endothelial progenitor cells derived small extracellular vesicles for spinal cord injury repair in mice].

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4.  Trends in the presentation and management of traumatic spinal cord lesions above T6: 20-Year experience in a tertiary-level hospital in Spain.

Authors:  Inés Esmorís Arijón; Rita Galeiras; Leticia Seoane Quiroga; María Elena Ferreiro Velasco; Sonia Pértega Díaz
Journal:  J Spinal Cord Med       Date:  2021-01-14       Impact factor: 2.040

5.  The effects of the M2a macrophage-induced axonal regeneration of neurons by arginase 1.

Authors:  Jieyuan Zhang; Yue Li; Zhaoxia Duan; Jianyi Kang; Kuijun Chen; Guanhua Li; Changmei Weng; Dongdong Zhang; Lu Zhang; Jianmin Wang; Bingcang Li
Journal:  Biosci Rep       Date:  2020-02-28       Impact factor: 3.840

6.  Promoting functions of microRNA-29a/199B in neurological recovery in rats with spinal cord injury through inhibition of the RGMA/STAT3 axis.

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7.  Prevalence, Incidence, and External Causes of Traumatic Spinal Cord Injury in China: A Nationally Representative Cross-Sectional Survey.

Authors:  Bin Jiang; Dongling Sun; Haixin Sun; Xiaojuan Ru; Hongmei Liu; Siqi Ge; Jie Fu; Wenzhi Wang
Journal:  Front Neurol       Date:  2022-01-20       Impact factor: 4.003

Review 8.  Progression in translational research on spinal cord injury based on microenvironment imbalance.

Authors:  Baoyou Fan; Zhijian Wei; Shiqing Feng
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9.  Research on Polycaprolactone-Gelatin Composite Scaffolds Carrying Nerve Growth Factor for the Repair of Spinal Cord Injury.

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  9 in total

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