| Literature DB >> 29323387 |
Xiupeng Wang1, Xia Li, Atsuo Ito, Yu Sogo, Yohei Watanabe, Kaoru Hashimoto, Atsushi Yamazaki, Tadao Ohno, Noriko M Tsuji.
Abstract
Stellated fibrous mesoporous silica nanospheres significantly improve the cellular uptake of cancer antigen and the maturation of bone marrow derived dendritic cells in vitro. Moreover, the combination of poly(I:C) with stellated fibrous MS nanospheres markedly decreases the necessary dose of poly(I:C) for anti-tumor immunity, and thus opens new opportunities for the future clinical application of poly(I:C) in cancer immunotherapy.Entities:
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Year: 2018 PMID： 29323387 DOI： 10.1039/c7cc08222c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222