| Literature DB >> 29317545 |
Gisli Thor Axelsson1,2, Rachel K Putman3, Tetsuro Araki4,5, Sigurdur Sigurdsson1, Elias Freyr Gudmundsson1, Gudny Eiriksdottir1, Thor Aspelund1,2, Ezra R Miller3, Lenore J Launer6, Tamara B Harris6, Hiroto Hatabu4,5, Vilmundur Gudnason1,2, Gary Matt Hunninghake3,5, Gunnar Gudmundsson2,7.
Abstract
We investigated the association between interstitial lung abnormalities (ILA) and self-reported measures of health and functional status in 5764 participants from the Age, Gene/Environment Susceptibility-Reykjavik study. The associations of ILA to activities of daily living (ADLs), general health status and physical activity were explored using logistic regression models. Participants with ILA were less likely to be independent in ADLs (OR 0.70; 95% CI 0.55 to 0.90) to have good or better self-reported health (OR 0.66; 95% CI 0.52 to 0.82) and to participate in physical activity (OR 0.72; CI 0.56 to 0.91). The results demonstrate ILA's association with worsening self-reported health and functional status. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Entities:
Keywords: idiopathic pulmonary fibrosis; imaging/ct mri etc; interstitial fibrosis
Mesh:
Year: 2018 PMID: 29317545 PMCID: PMC6037567 DOI: 10.1136/thoraxjnl-2017-210956
Source DB: PubMed Journal: Thorax ISSN: 0040-6376 Impact factor: 9.139